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G. P. kolena
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Site-specific mutagenesis in Escherichia coli by N2-deoxyguanosine adducts derived from the highly carcinogenic fjord-region benzo[c]phenanthrene 3,4-diol 1,2-epoxides.
Chem Res Toxicol. 2002 Dec;15(12):1619-26. doi: 10.1021/tx020073r.
Chem Res Toxicol. 2002.
PMID: 12482245
For all but this last adduct, the mutation frequency for a given B[c]Ph DE adduct was less than for its B[a]P analogue with the same stereochemistry in the same sequence. For the vectors containing adducts with S configuration at the site of attachment of the hydrocarbon t …
For all but this last adduct, the mutation frequency for a given B[c]Ph DE adduct was less than for its B[a]P analogue with the same …
Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications.
Yakovleva L, Tian L, Sayer JM, Kalena GP, Kroth H, Jerina DM, Shuman S.
Yakovleva L, et al.
J Biol Chem. 2003 Oct 24;278(43):42170-7. doi: 10.1074/jbc.M308079200. Epub 2003 Aug 8.
J Biol Chem. 2003.
PMID: 12909623
Free article.
Chiral trans opened C-10 R and S adducts of benzo[a]pyrene (BP) 7,8-diol 9,10-epoxide were introduced at single N6-deoxyadenosine (dA) positions within the 3'-G+5G+4G+3A+2A+1T-1A-2 sequence of the nonscissile DNA strand. The R and S BPdA adducts intercalate from the major …
Chiral trans opened C-10 R and S adducts of benzo[a]pyrene (BP) 7,8-diol 9,10-epoxide were introduced at single N6-deoxyadenosine (dA) posit …
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