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Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma.
Mellinghoff IK, van den Bent MJ, Blumenthal DT, Touat M, Peters KB, Clarke J, Mendez J, Yust-Katz S, Welsh L, Mason WP, Ducray F, Umemura Y, Nabors B, Holdhoff M, Hottinger AF, Arakawa Y, Sepulveda JM, Wick W, Soffietti R, Perry JR, Giglio P, de la Fuente M, Maher EA, Schoenfeld S, Zhao D, Pandya SS, Steelman L, Hassan I, Wen PY, Cloughesy TF; INDIGO Trial Investigators. Mellinghoff IK, et al. N Engl J Med. 2023 Aug 17;389(7):589-601. doi: 10.1056/NEJMoa2304194. Epub 2023 Jun 4. N Engl J Med. 2023. PMID: 37272516 Clinical Trial.
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen KB, Wollmuth LP, Bowie D, Furukawa H, Menniti FS, Sobolevsky AI, Swanson GT, Swanger SA, Greger IH, Nakagawa T, McBain CJ, Jayaraman V, Low CM, Dell'Acqua ML, Diamond JS, Camp CR, Perszyk RE, Yuan H, Traynelis SF. Hansen KB, et al. Pharmacol Rev. 2021 Oct;73(4):298-487. doi: 10.1124/pharmrev.120.000131. Pharmacol Rev. 2021. PMID: 34753794 Free PMC article. Review.
Erratum for the Technical Comment "Comment on 'Principles of connectivity among morphologically defined cell types in adult neocortex'" by A. L. Barth, A. Burkhalter, E. M. Callaway, B. W. Connors, B. Cauli, J. DeFelipe, D. Feldmeyer, T. Freund, Y. Kawaguchi, Z. Kisvarday, Y. Kubota, C. McBain, M. Oberlaender, J. Rossier, B. Rudy, J. F. Staiger, P. Somogyi, G. Tamas, R. Yuste.
[No authors listed] [No authors listed] Science. 2016 Sep 23;353(6306):aaj2094. doi: 10.1126/science.aaj2094. Science. 2016. PMID: 27708009 No abstract available.
Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more).
Middleton P, Shepherd E, Flenady V, McBain RD, Crowther CA. Middleton P, et al. Cochrane Database Syst Rev. 2017 Jan 4;1(1):CD005302. doi: 10.1002/14651858.CD005302.pub3. Cochrane Database Syst Rev. 2017. PMID: 28050900 Free PMC article. Review.
It is not clear if waiting for birth to occur spontaneously is better than intervening, e.g. by inducing labour. OBJECTIVES: The objective of this review is to assess the effects of planned early birth (immediate intervention or intervention within 24 hours) when compared …
It is not clear if waiting for birth to occur spontaneously is better than intervening, e.g. by inducing labour. OBJECTIVES: The obje …
Anti-D administration in pregnancy for preventing Rhesus alloimmunisation.
Crowther CA, Middleton P, McBain RD. Crowther CA, et al. Cochrane Database Syst Rev. 2013 Feb 28;(2):CD000020. doi: 10.1002/14651858.CD000020.pub2. Cochrane Database Syst Rev. 2013. PMID: 23450526 Updated. Review.
SELECTION CRITERIA: Randomised trials in Rh-negative women without anti-D antibodies given anti-D after 28 weeks of pregnancy, compared with no treatment, placebo or a different regimen of anti-D. ...Administration of 100 g (500 IU) anti-D to wo …
SELECTION CRITERIA: Randomised trials in Rh-negative women without anti-D antibodies given anti-D after 28 weeks of pregnancy, …
The clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis.
Gregory GE, Islim AI, Hannan CJ, Jones AP, Hammerbeck-Ward C, Rutherford SA, Freeman SR, Lloyd S, Kalamarides M, Smith MJ, Couper K, McBain CA, Jenkinson MD, Brough D, King AT, Evans DG, Pathmanaban ON. Gregory GE, et al. Neurooncol Adv. 2023 Jun 3;5(Suppl 1):i94-i104. doi: 10.1093/noajnl/vdac127. eCollection 2023 May. Neurooncol Adv. 2023. PMID: 37287576 Free PMC article.
Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function.
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Falco MM, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, Morales DK, Rodriguez PC, Conejo-Garcia JR, Kaczocha M, Vähärautio A, Song M, Cubillos-Ruiz JR. Hwang SM, et al. Res Sq [Preprint]. 2023 Dec 14:rs.3.rs-3683989. doi: 10.21203/rs.3.rs-3683989/v1. Res Sq. 2023. PMID: 38168227 Free PMC article. Preprint.
Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons.
Camp CR, Vlachos A, Klöckner C, Krey I, Banke TG, Shariatzadeh N, Ruggiero SM, Galer P, Park KL, Caccavano A, Kimmel S, Yuan X, Yuan H, Helbig I, Benke TA, Lemke JR, Pelkey KA, McBain CJ, Traynelis SF. Camp CR, et al. Commun Biol. 2023 Sep 19;6(1):952. doi: 10.1038/s42003-023-05298-9. Commun Biol. 2023. PMID: 37723282 Free PMC article.
N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ionotropic glutamate receptors that mediate a calcium-permeable component to fast excitatory neurotransmission. ...
N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ionotropic glutamate receptors that mediate a calcium-permeable component to …
A versatile viral toolkit for functional discovery in the nervous system.
Pouchelon G, Vergara J, McMahon J, Gorissen BL, Lin JD, Vormstein-Schneider D, Niehaus JL, Burbridge TJ, Wester JC, Sherer M, Fernandez-Otero M, Allaway KC, Pelkey K, Chittajallu R, McBain CJ, Fan M, Nasse JS, Wildenberg GA, Fishell G, Dimidschstein J. Pouchelon G, et al. Cell Rep Methods. 2022 May 26;2(6):100225. doi: 10.1016/j.crmeth.2022.100225. eCollection 2022 Jun 20. Cell Rep Methods. 2022. PMID: 35784651 Free PMC article.
Combination of a pH-responsive peptide amphiphile and a conventional antibiotic in treating Gram-negative bacteria.
Liao M, Gong H, Liu H, Shen K, Ge T, King S, Schweins R, McBain AJ, Hu X, Lu JR. Liao M, et al. J Colloid Interface Sci. 2024 Apr;659:397-412. doi: 10.1016/j.jcis.2023.12.146. Epub 2023 Dec 28. J Colloid Interface Sci. 2024. PMID: 38183806 Free article.
EXPERIMENTS: Using a combined approach of cell assays, molecular dynamics (MD) simulations and membrane models facilitating biophysical and biochemical measurements including small angle neutron scattering (SANS), we have characterized the pH-responsive physiochemical properties …
EXPERIMENTS: Using a combined approach of cell assays, molecular dynamics (MD) simulations and membrane models facilitating biophysical and …
19 results