Search Page
Filters
Results by year
Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2005 | 1 |
2007 | 2 |
2008 | 1 |
2010 | 1 |
2011 | 2 |
2012 | 1 |
2015 | 2 |
2017 | 1 |
2018 | 2 |
2021 | 1 |
2024 | 0 |
Search Results
14 results
Results by year
Page 1
Synthesis and SAR of novel 4-morpholinopyrrolopyrimidine derivatives as potent phosphatidylinositol 3-kinase inhibitors.
J Med Chem. 2010 Apr 22;53(8):3169-82. doi: 10.1021/jm901783v.
J Med Chem. 2010.
PMID: 20334367
A series of 4-morpholinopyrrolopyrimidine derivatives were synthesized and evaluated as inhibitors of PI3Kalpha and mTOR, leading to the discovery of PI3Kalpha selective inhibitors (e.g., 9) and dual PI3Kalpha/mTOR kinase inhibitors (e.g., 46 and 48). PI3Kalpha/mTOR …
A series of 4-morpholinopyrrolopyrimidine derivatives were synthesized and evaluated as inhibitors of PI3Kalpha and mTOR, leading to the dis …
Inside the mind of a medicinal chemist: the role of human bias in compound prioritization during drug discovery.
PLoS One. 2012;7(11):e48476. doi: 10.1371/journal.pone.0048476. Epub 2012 Nov 21.
PLoS One. 2012.
PMID: 23185259
Free PMC article.
Identification of 2-oxatriazines as highly potent pan-PI3K/mTOR dual inhibitors.
Bioorg Med Chem Lett. 2011 Aug 15;21(16):4773-8. doi: 10.1016/j.bmcl.2011.06.063. Epub 2011 Jun 21.
Bioorg Med Chem Lett. 2011.
PMID: 21763134
We recently described several highly potent, triazine (1) and triazolopyrimidine (2) scaffold-based, dual PI3K/mTOR-inhibitors (e.g., 1, PKI-587) that were efficacious in both in vitro and in vivo models. ...
We recently described several highly potent, triazine (1) and triazolopyrimidine (2) scaffold-based, dual PI3K/mTOR-inhibitors (e.g., …
Search for New Phenomena in Final States with Two Leptons and One or No b-Tagged Jets at sqrt[s]=13 TeV Using the ATLAS Detector.
Phys Rev Lett. 2021 Oct 1;127(14):141801. doi: 10.1103/PhysRevLett.127.141801.
Phys Rev Lett. 2021.
PMID: 34652194
Free article.
Inspired by the B-meson decay anomalies, a four-fermion contact interaction between two quarks (b, s) and two leptons (ee or mumu) is used as a benchmark signal model, which is characterized by the energy scale and coupling, lambda and g_{*}, respectively. Contact interact …
Inspired by the B-meson decay anomalies, a four-fermion contact interaction between two quarks (b, s) and two leptons (ee or mumu) is used a …
Search for High-Mass Resonances Decaying to τν in pp Collisions at sqrt[s]=13 TeV with the ATLAS Detector.
Phys Rev Lett. 2018 Apr 20;120(16):161802. doi: 10.1103/PhysRevLett.120.161802.
Phys Rev Lett. 2018.
PMID: 29756910
Free article.
Heavy W^{'} bosons with masses less than 3.7 TeV in the sequential standard model and masses less than 2.2-3.8 TeV depending on the coupling in the nonuniversal G(221) model are excluded at the 95% credibility level....
Heavy W^{'} bosons with masses less than 3.7 TeV in the sequential standard model and masses less than 2.2-3.8 TeV depending on the coupling …
Search for Resonant and Nonresonant Higgs Boson Pair Production in the bb[over ¯]τ^{+}τ^{-} Decay Channel in pp Collisions at sqrt[s]=13 TeV with the ATLAS Detector.
Phys Rev Lett. 2018 Nov 9;121(19):191801. doi: 10.1103/PhysRevLett.121.191801.
Phys Rev Lett. 2018.
PMID: 30468613
Free article.
Upper limits are placed on the resonant Higgs boson pair production cross-section times branching ratio, excluding resonances X in the mass range 305 GeV
Upper limits are placed on the resonant Higgs boson pair production cross-section times branching ratio, excluding resonances X in the mass …
Search for new phenomena in events containing a same-flavour opposite-sign dilepton pair, jets, and large missing transverse momentum in [Formula: see text] [Formula: see text][Formula: see text] collisions with the ATLAS detector.
Eur Phys J C Part Fields. 2017;77(3):144. doi: 10.1140/epjc/s10052-017-4700-5. Epub 2017 Mar 4.
Eur Phys J C Part Fields. 2017.
PMID: 28690423
Free PMC article.
Both searches target the pair production of supersymmetric particles, squarks or gluinos, which decay to final states containing a same-flavour opposite-sign lepton pair via one of two mechanisms: a leptonically decaying Z boson in the final state, leading to a peak in the dilept …
Both searches target the pair production of supersymmetric particles, squarks or gluinos, which decay to final states containing a same-flav …
Combined Measurement of the Higgs Boson Mass in pp Collisions at sqrt[s]=7 and 8 TeV with the ATLAS and CMS Experiments.
Phys Rev Lett. 2015 May 15;114(19):191803. doi: 10.1103/PhysRevLett.114.191803. Epub 2015 May 14.
Phys Rev Lett. 2015.
PMID: 26024162
Free article.
Search for production of single top quarks via tcg and tug flavor-changing-neutral-current couplings.
Phys Rev Lett. 2007 Nov 9;99(19):191802. doi: 10.1103/PhysRevLett.99.191802. Epub 2007 Nov 6.
Phys Rev Lett. 2007.
PMID: 18233063
We observe no significant deviation from standard model predictions, and hence set upper limits on the anomalous coupling parameters kappa{g}{c}/Lambda and kappa{g}{u}/Lambda, where kappa{g} define the strength of tcg and tug couplings, and Lambda defines the …
We observe no significant deviation from standard model predictions, and hence set upper limits on the anomalous coupling parameters kappa{ …
Search for Resonant WW and WZ Production in pp collisions at √s=1.96 TeV.
Phys Rev Lett. 2011 Jul 1;107(1):011801. doi: 10.1103/PhysRevLett.107.011801. Epub 2011 Jun 29.
Phys Rev Lett. 2011.
PMID: 21797534
The data are consistent with the standard model background expectation, and we set limits on a resonance mass by using the sequential standard model W' boson and the Randall-Sundrum model graviton G as benchmarks. We exclude a sequential standard model W' boson in the mass …
The data are consistent with the standard model background expectation, and we set limits on a resonance mass by using the sequential standa …
Cite