In this study, a polarization-control setup for intensity-resolved guided mode resonance sensors is proposed and demonstrated experimentally. The experimental results are in good agreement with the simulation data based on rigorous coupled wave approach calculations. The proposed intensity-resolved measurement setup transfers polarization ellipses, which are produced from guided mode resonance to a linear polarization state under a buffer solution condition, and then suppresses the signals to dark using a polarization-control set. Hence, any changes in the refractive index results in an increase in the intensity signals. Furthermore, no wavelength-resolved or angular-resolved measurement is needed in this scheme. According to the experimental results, a wide linear detection range of 0.014 refractive index units is achieved and the limit of detection is 1.62E-4 RIU.