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Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations.
Wang JQ, He ZC, Peng W, Han TH, Mei Q, Wang QZ, Ding F. Wang JQ, et al. Chem Res Toxicol. 2023 Mar 20;36(3):535-551. doi: 10.1021/acs.chemrestox.2c00418. Epub 2023 Feb 17. Chem Res Toxicol. 2023. PMID: 36799861
Cell-based assays indicate that chiral isocarbophos exhibits strong enantioselectivity in the inhibition of the survival rates of SH-SY5Y cells and the intracellular AChE activity, and the cytotoxicity of (S)-isocarbophos is significantly greater than that of (R)-isocarbop …
Cell-based assays indicate that chiral isocarbophos exhibits strong enantioselectivity in the inhibition of the survival rates of SH-SY5Y ce …
Study on the interaction of chromate with bovine serum albumin by spectroscopic method.
Cao H, Yi Y. Cao H, et al. Biometals. 2017 Aug;30(4):529-539. doi: 10.1007/s10534-017-0022-1. Epub 2017 May 18. Biometals. 2017. PMID: 28523598
The thermodynamic parameters enthalpy change (deltaH), entropy change (deltaS) were negative, indicating that the interaction of two chromates with BSA was driven mainly by van der Waals forces and hydrogen bonds. The process of binding was a spontaneous process in which G …
The thermodynamic parameters enthalpy change (deltaH), entropy change (deltaS) were negative, indicating that the interaction of two chromat …