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Page 1
ROS Modulator Molecules with Therapeutic Potential in Cancers Treatments.
Nicco C, Batteux F. Nicco C, et al. Molecules. 2017 Dec 31;23(1):84. doi: 10.3390/molecules23010084. Molecules. 2017. PMID: 29301225 Free PMC article. Review.
Reactive Oxygen Species (ROS) are chemically reactive chemical species containing oxygen. The redox status of a cell is function of the relative concentrations of oxidized and reduced forms of proteins, enzymes, ROS, molecules containing thiol and other factors. In …
Reactive Oxygen Species (ROS) are chemically reactive chemical species containing oxygen. The redox status of a cell is function of t …
UCPs, at the interface between bioenergetics and metabolism.
Bouillaud F, Alves-Guerra MC, Ricquier D. Bouillaud F, et al. Biochim Biophys Acta. 2016 Oct;1863(10):2443-56. doi: 10.1016/j.bbamcr.2016.04.013. Epub 2016 Apr 16. Biochim Biophys Acta. 2016. PMID: 27091404 Free article. Review.
Complete energy conservation loss would be fatal but fine-tuning can be beneficial for processes such as thermogenesis, redox control, and prevention of mitochondrial ROS release. The coupled/uncoupled state of mitochondria is related to the permeability of the inner membr …
Complete energy conservation loss would be fatal but fine-tuning can be beneficial for processes such as thermogenesis, redox control, and p …
Leflunomide prevents ROS-induced systemic fibrosis in mice.
Morin F, Kavian N, Chouzenoux S, Cerles O, Nicco C, Chéreau C, Batteux F. Morin F, et al. Free Radic Biol Med. 2017 Jul;108:192-203. doi: 10.1016/j.freeradbiomed.2017.03.035. Epub 2017 Mar 30. Free Radic Biol Med. 2017. PMID: 28365359
UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing.
Bouillaud F. Bouillaud F. Biochim Biophys Acta. 2009 May;1787(5):377-83. doi: 10.1016/j.bbabio.2009.01.003. Epub 2009 Jan 20. Biochim Biophys Acta. 2009. PMID: 19413946 Free article. Review.
Accordingly, it was proposed that UCP2 and UCP3 are also uncoupling proteins i.e. protonophores with impact on mitochondrial ROS production and glucose signaling. However, it appears now impossible to explain the physiological relevance of the new UCPs uniquely by their un …
Accordingly, it was proposed that UCP2 and UCP3 are also uncoupling proteins i.e. protonophores with impact on mitochondrial ROS prod …
New insights on chemically induced animal models of systemic sclerosis.
Batteux F, Kavian N, Servettaz A. Batteux F, et al. Curr Opin Rheumatol. 2011 Nov;23(6):511-8. doi: 10.1097/BOR.0b013e32834b1606. Curr Opin Rheumatol. 2011. PMID: 21857225 Review.
SUMMARY: Chemically induced models truly develop a SSc-like disease and argue for a crucial role of ROS in SSc....
SUMMARY: Chemically induced models truly develop a SSc-like disease and argue for a crucial role of ROS in SSc....
Reactive Oxygen Species Modulate Activity-Dependent AMPA Receptor Transport in C. elegans.
Doser RL, Amberg GC, Hoerndli FJ. Doser RL, et al. J Neurosci. 2020 Sep 23;40(39):7405-7420. doi: 10.1523/JNEUROSCI.0902-20.2020. Epub 2020 Aug 26. J Neurosci. 2020. PMID: 32847966 Free PMC article.
Aerobic ATP synthesis unavoidably produces reactive oxygen species (ROS), such as hydrogen peroxide, which are known modulators of calcium signaling. ...By combining genetic and pharmacological manipulation of ROS levels and calcium influx, we reveal a mechanism in …
Aerobic ATP synthesis unavoidably produces reactive oxygen species (ROS), such as hydrogen peroxide, which are known modulators of ca …
Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase.
Wargnies M, Plazolles N, Schenk R, Villafraz O, Dupuy JW, Biran M, Bachmaier S, Baudouin H, Clayton C, Boshart M, Bringaud F. Wargnies M, et al. J Biol Chem. 2021 Jan-Jun;296:100548. doi: 10.1016/j.jbc.2021.100548. Epub 2021 Mar 17. J Biol Chem. 2021. PMID: 33741344 Free PMC article.
Hence, growth retardation is interpreted as a consequence of increased production of ROS, and rearrangement of the FRD locus liberates deltapepck cells from this obstacle. Interestingly, intracellular production of ROS has been shown to be required to complete the p …
Hence, growth retardation is interpreted as a consequence of increased production of ROS, and rearrangement of the FRD locus liberate …
Role of thyroid dysimmunity and thyroid hormones in endometriosis.
Peyneau M, Kavian N, Chouzenoux S, Nicco C, Jeljeli M, Toullec L, Reboul-Marty J, Chenevier-Gobeaux C, Reis FM, Santulli P, Doridot L, Chapron C, Batteux F. Peyneau M, et al. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11894-11899. doi: 10.1073/pnas.1820469116. Epub 2019 May 29. Proc Natl Acad Sci U S A. 2019. PMID: 31142643 Free PMC article.
Thyroid-stimulating hormone (TSH) acts as a proliferative and prooxidative hormone on all endometria of endometriosis patients and controls, whereas T3 and T4 act to specifically increase ectopic endometrial cell proliferation and reactive oxygen species (ROS) production. …
Thyroid-stimulating hormone (TSH) acts as a proliferative and prooxidative hormone on all endometria of endometriosis patients and controls, …
31 results