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Showing results for franco lombardo
Search for Franco Lombardi instead (1 results)
The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1.
Wylie AA, Schoepfer J, Jahnke W, Cowan-Jacob SW, Loo A, Furet P, Marzinzik AL, Pelle X, Donovan J, Zhu W, Buonamici S, Hassan AQ, Lombardo F, Iyer V, Palmer M, Berellini G, Dodd S, Thohan S, Bitter H, Branford S, Ross DM, Hughes TP, Petruzzelli L, Vanasse KG, Warmuth M, Hofmann F, Keen NJ, Sellers WR. Wylie AA, et al. Among authors: lombardo f. Nature. 2017 Mar 30;543(7647):733-737. doi: 10.1038/nature21702. Epub 2017 Mar 22. Nature. 2017. PMID: 28329763
Hydrolysis in pharmaceutical formulations.
Waterman KC, Adami RC, Alsante KM, Antipas AS, Arenson DR, Carrier R, Hong J, Landis MS, Lombardo F, Shah JC, Shalaev E, Smith SW, Wang H. Waterman KC, et al. Among authors: lombardo f. Pharm Dev Technol. 2002 May;7(2):113-46. doi: 10.1081/pdt-120003494. Pharm Dev Technol. 2002. PMID: 12066569 Review.
Stabilization of pharmaceuticals to oxidative degradation.
Waterman KC, Adami RC, Alsante KM, Hong J, Landis MS, Lombardo F, Roberts CJ. Waterman KC, et al. Among authors: lombardo f. Pharm Dev Technol. 2002 Jan;7(1):1-32. doi: 10.1081/pdt-120002237. Pharm Dev Technol. 2002. PMID: 11852692 Review.
In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development.
Lombardo F, Desai PV, Arimoto R, Desino KE, Fischer H, Keefer CE, Petersson C, Winiwarter S, Broccatelli F. Lombardo F, et al. J Med Chem. 2017 Nov 22;60(22):9097-9113. doi: 10.1021/acs.jmedchem.7b00487. Epub 2017 Jun 27. J Med Chem. 2017. PMID: 28609624 Review.
Antibacterial and Solubility Optimization of Thiomuracin A.
LaMarche MJ, Leeds JA, Brewer J, Dean K, Ding J, Dzink-Fox J, Gamber G, Jain A, Kerrigan R, Krastel P, Lee K, Lombardo F, McKenney D, Neckermann G, Osborne C, Palestrant D, Patane MA, Rann EM, Robinson Z, Schmitt E, Stams T, Tiamfook S, Yu D, Whitehead L. LaMarche MJ, et al. Among authors: lombardo f. J Med Chem. 2016 Jul 28;59(14):6920-8. doi: 10.1021/acs.jmedchem.6b00726. Epub 2016 Jul 12. J Med Chem. 2016. PMID: 27355833
Benefit of Retraining pKa Models Studied Using Internally Measured Data.
Gedeck P, Lu Y, Skolnik S, Rodde S, Dollinger G, Jia W, Berellini G, Vianello R, Faller B, Lombardo F. Gedeck P, et al. Among authors: lombardo f. J Chem Inf Model. 2015 Jul 27;55(7):1449-59. doi: 10.1021/acs.jcim.5b00172. Epub 2015 Jun 29. J Chem Inf Model. 2015. PMID: 26052622
Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.
Garcia Fortanet J, Chen CH, Chen YN, Chen Z, Deng Z, Firestone B, Fekkes P, Fodor M, Fortin PD, Fridrich C, Grunenfelder D, Ho S, Kang ZB, Karki R, Kato M, Keen N, LaBonte LR, Larrow J, Lenoir F, Liu G, Liu S, Lombardo F, Majumdar D, Meyer MJ, Palermo M, Perez L, Pu M, Ramsey T, Sellers WR, Shultz MD, Stams T, Towler C, Wang P, Williams SL, Zhang JH, LaMarche MJ. Garcia Fortanet J, et al. Among authors: lombardo f. J Med Chem. 2016 Sep 8;59(17):7773-82. doi: 10.1021/acs.jmedchem.6b00680. Epub 2016 Jul 12. J Med Chem. 2016. PMID: 27347692
In silico prediction of total human plasma clearance.
Berellini G, Waters NJ, Lombardo F. Berellini G, et al. Among authors: lombardo f. J Chem Inf Model. 2012 Aug 27;52(8):2069-78. doi: 10.1021/ci300155y. Epub 2012 Jul 18. J Chem Inf Model. 2012. PMID: 22715914
35 results