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An organoid model of colorectal circulating tumor cells with stem cell features, hybrid EMT state and distinctive therapy response profile.
De Angelis ML, Francescangeli F, Nicolazzo C, Signore M, Giuliani A, Colace L, Boe A, Magri V, Baiocchi M, Ciardi A, Scarola F, Spada M, La Torre F, Gazzaniga P, Biffoni M, De Maria R, Zeuner A. De Angelis ML, et al. J Exp Clin Cancer Res. 2022 Mar 8;41(1):86. doi: 10.1186/s13046-022-02263-y. J Exp Clin Cancer Res. 2022. PMID: 35260172 Free PMC article.
A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer.
Francescangeli F, Contavalli P, De Angelis ML, Careccia S, Signore M, Haas TL, Salaris F, Baiocchi M, Boe A, Giuliani A, Tcheremenskaia O, Pagliuca A, Guardiola O, Minchiotti G, Colace L, Ciardi A, D'Andrea V, La Torre F, Medema J, De Maria R, Zeuner A. Francescangeli F, et al. J Exp Clin Cancer Res. 2020 Jan 8;39(1):2. doi: 10.1186/s13046-019-1505-4. J Exp Clin Cancer Res. 2020. PMID: 31910865 Free PMC article.