Abstract
This report describe the case of a patient presenting with pulmonary metastases from a penile cancer, where the presence of the human papillomavirus (HPV) type 16 DNA both in the primary tumor and in the distant metastases confirmed the spreading of the disease, ruling out a possible primary lung squamous cell carcinoma. Indeed, according to the findings, the HPV genotyping test might help in the identification of metastatic disease from anogenital malignancies or other HPV-related cancers.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Carcinoma, Squamous Cell / diagnosis
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Carcinoma, Squamous Cell / secondary
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Carcinoma, Squamous Cell / virology*
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DNA, Viral / genetics
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DNA, Viral / isolation & purification*
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Diagnosis, Differential
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Fatal Outcome
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Human papillomavirus 16 / genetics
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Human papillomavirus 16 / isolation & purification*
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Humans
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Lung Neoplasms / diagnosis
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Lung Neoplasms / secondary
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Lung Neoplasms / virology*
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Male
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Papillomavirus Infections / complications*
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Papillomavirus Infections / pathology
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Penile Neoplasms / pathology
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Penile Neoplasms / virology*
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Tomography, X-Ray Computed