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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
2001 2
2002 1
2009 1
2012 1
2014 1
2016 1
2017 1
2018 1
2019 1
2020 2
2022 1
2023 1
2024 0

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15 results

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Page 1
Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial.
Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, Hibbert S, Budnik N, Zampedri L, Dickson J, Li Y, Aviles-Olmos I, Warner TT, Limousin P, Lees AJ, Greig NH, Tebbs S, Foltynie T. Athauda D, et al. Lancet. 2017 Oct 7;390(10103):1664-1675. doi: 10.1016/S0140-6736(17)31585-4. Epub 2017 Aug 3. Lancet. 2017. PMID: 28781108 Free PMC article. Clinical Trial.
Six serious adverse events occurred in the exenatide group and two in the placebo group, although none in either group were judged to be related to the study interventions. INTERPRETATION: Exenatide had positive effects on practically defined off-medication motor scores in …
Six serious adverse events occurred in the exenatide group and two in the placebo group, although none in either group were judged to …
3D printing and high tibial osteotomy.
Jones GG, Jaere M, Clarke S, Cobb J. Jones GG, et al. EFORT Open Rev. 2018 May 21;3(5):254-259. doi: 10.1302/2058-5241.3.170075. eCollection 2018 May. EFORT Open Rev. 2018. PMID: 29951264 Free PMC article.
Thus far, the outcomes have been variable, and apparently worse than the arthroplasty alternatives when judged using conventional metrics, owing in large part to uncertainty around the extent of the correction planned and achieved.This review paper introduces the concept o …
Thus far, the outcomes have been variable, and apparently worse than the arthroplasty alternatives when judged using conventional met …
Cryo-Electron Microscopy Structure of the αIIbβ3-Abciximab Complex.
Nešić D, Zhang Y, Spasic A, Li J, Provasi D, Filizola M, Walz T, Coller BS. Nešić D, et al. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):624-637. doi: 10.1161/ATVBAHA.119.313671. Epub 2020 Jan 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 31969014 Free PMC article.
Unexpectedly, the structure also indicated several interactions with alphaIIb. As judged by the cryo-electron microscopy model, molecular-dynamics simulations, and mutagenesis, the binding of abciximab does not appear to rely on the interaction with the alphaIIb residues a …
Unexpectedly, the structure also indicated several interactions with alphaIIb. As judged by the cryo-electron microscopy model, molec …
Codeine, alone and with paracetamol (acetaminophen), for cancer pain.
Straube C, Derry S, Jackson KC, Wiffen PJ, Bell RF, Strassels S, Straube S. Straube C, et al. Cochrane Database Syst Rev. 2014 Sep 19;2014(9):CD006601. doi: 10.1002/14651858.CD006601.pub4. Cochrane Database Syst Rev. 2014. PMID: 25234029 Free PMC article. Review.
The included studies were of adequate methodological quality, but all except for one were judged to be at a high risk of bias because of small study size, and six because of methods used to deal with missing data or high withdrawal rates. ...
The included studies were of adequate methodological quality, but all except for one were judged to be at a high risk of bias because …
Colloid solutions for fluid resuscitation.
Bunn F, Alderson P, Hawkins V. Bunn F, et al. Cochrane Database Syst Rev. 2001;(2):CD001319. doi: 10.1002/14651858.CD001319. Cochrane Database Syst Rev. 2001. PMID: 11405985 Updated. Review.
MAIN RESULTS: 52 trials met the inclusion criteria, with a total of 3311 participants. Quality of allocation concealment was judged to be adequate in 17 trials and poor or uncertain in 35. Deaths were obtained from 31 trials. ...
MAIN RESULTS: 52 trials met the inclusion criteria, with a total of 3311 participants. Quality of allocation concealment was judged t …
Structure-Based Discovery of a Novel Class of Small-Molecule Pure Antagonists of Integrin αVβ3.
Sen S, Spasic A, Sinha A, Wang J, Bush M, Li J, Nešić D, Zhou Y, Angiulli G, Morgan P, Salas-Estrada L, Takagi J, Walz T, Coller BS, Filizola M. Sen S, et al. J Chem Inf Model. 2022 Nov 28;62(22):5607-5621. doi: 10.1021/acs.jcim.2c00999. Epub 2022 Oct 24. J Chem Inf Model. 2022. PMID: 36279366 Free PMC article.
Functional and structural characterization of a chemically optimized version of this compound led to the discovery of a novel small-molecule pure alphaVbeta3 antagonist that (i) does not prime the receptor to bind the ligand and does not induce hybrid domain swing-out or receptor …
Functional and structural characterization of a chemically optimized version of this compound led to the discovery of a novel small-molecule …
Automating weighing of faces and voices based on cue saliency in trustworthiness impressions.
Vives ML, Frances C, Baus C. Vives ML, et al. Sci Rep. 2023 Nov 16;13(1):20037. doi: 10.1038/s41598-023-45471-y. Sci Rep. 2023. PMID: 37973908 Free PMC article.
We find that, even though participants can focus their attention on one modality to judge trustworthiness, they fail to completely filter out the other modality for both faces (Experiment 1a) and voices (Experiment 1b). When asked to judge the person as a whole, peo …
We find that, even though participants can focus their attention on one modality to judge trustworthiness, they fail to completely fi …
What Do Infants Really Eat?
Ryan C, Dwyer J, Ziegler P, Yang E, Moore L, Song WO. Ryan C, et al. Nutr Today. 2002 Mar-Apr;37(2):50-56. doi: 10.1097/00017285-200203000-00004. Nutr Today. 2002. PMID: 11984433
Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations.
Li J, Fukase Y, Shang Y, Zou W, Muñoz-Félix JM, Buitrago L, van Agthoven J, Zhang Y, Hara R, Tanaka Y, Okamoto R, Yasui T, Nakahata T, Imaeda T, Aso K, Zhou Y, Locuson C, Nesic D, Duggan M, Takagi J, Vaughan RD, Walz T, Hodivala-Dilke K, Teitelbaum SL, Arnaout MA, Filizola M, Foley MA, Coller BS. Li J, et al. ACS Pharmacol Transl Sci. 2019 Aug 2;2(6):387-401. doi: 10.1021/acsptsci.9b00041. eCollection 2019 Dec 13. ACS Pharmacol Transl Sci. 2019. PMID: 32259072 Free PMC article.
Both compounds inhibit alphaVbeta3-mediated cell adhesion to alphaVbeta3 ligands, but do not induce the conformational change as judged by antibody binding, electron microscopy, X-ray crystallography, and receptor priming studies. ...
Both compounds inhibit alphaVbeta3-mediated cell adhesion to alphaVbeta3 ligands, but do not induce the conformational change as judged …
A role for judges in assisted dying.
Castelló A, Francès F, Verdú F. Castelló A, et al. J Med Ethics Hist Med. 2009 May 30;2:3. Print 2009. J Med Ethics Hist Med. 2009. PMID: 23908717 Free PMC article.
15 results