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4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.
Verhaeghe P, Dumètre A, Castera-Ducros C, Hutter S, Laget M, Fersing C, Prieri M, Yzombard J, Sifredi F, Rault S, Rathelot P, Vanelle P, Azas N. Verhaeghe P, et al. Among authors: sifredi f. Bioorg Med Chem Lett. 2011 Oct 1;21(19):6003-6. doi: 10.1016/j.bmcl.2011.06.113. Epub 2011 Jul 2. Bioorg Med Chem Lett. 2011. PMID: 21852132
Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series.
Castera-Ducros C, Azas N, Verhaeghe P, Hutter S, Garrigue P, Dumètre A, Mbatchi L, Laget M, Remusat V, Sifredi F, Rault S, Rathelot P, Vanelle P. Castera-Ducros C, et al. Among authors: sifredi f. Eur J Med Chem. 2011 Sep;46(9):4184-91. doi: 10.1016/j.ejmech.2011.06.021. Epub 2011 Jun 23. Eur J Med Chem. 2011. PMID: 21741131