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Targeting Transcriptional Enhanced Associate Domains (TEADs).
J Med Chem. 2018 Jun 28;61(12):5057-5072. doi: 10.1021/acs.jmedchem.7b00879. Epub 2017 Dec 28.
J Med Chem. 2018.
PMID: 29251924
Review.
Non-Photoinduced Biological Properties of Verteporfin.
Gibault F, Corvaisier M, Bailly F, Huet G, Melnyk P, Cotelle P.
Gibault F, et al.
Curr Med Chem. 2016;23(11):1171-84. doi: 10.2174/0929867323666160316125048.
Curr Med Chem. 2016.
PMID: 26980565
Review.
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Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.
Gibault F, Sturbaut M, Coevoet M, Pugnière M, Burtscher A, Allemand F, Melnyk P, Hong W, Rubin BP, Pobbati AV, Guichou JF, Cotelle P, Bailly F.
Gibault F, et al.
ChemMedChem. 2021 Sep 16;16(18):2823-2844. doi: 10.1002/cmdc.202100153. Epub 2021 Jul 1.
ChemMedChem. 2021.
PMID: 34032019
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Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.
Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P.
Gibault F, et al.
Cancers (Basel). 2018 May 8;10(5):140. doi: 10.3390/cancers10050140.
Cancers (Basel). 2018.
PMID: 29738494
Free PMC article.
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Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.
Gibault F, Bailly F, Corvaisier M, Coevoet M, Huet G, Melnyk P, Cotelle P.
Gibault F, et al.
ChemMedChem. 2017 Jun 21;12(12):954-961. doi: 10.1002/cmdc.201700063. Epub 2017 Apr 20.
ChemMedChem. 2017.
PMID: 28334506
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