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A 2',2'-disulfide-bridged dinucleotide conformationally locks RNA hairpins.
Org Biomol Chem. 2018 May 2;16(17):3181-3188. doi: 10.1039/c8ob00328a.
Org Biomol Chem. 2018.
PMID: 29645048
Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers.
Gauthier F, Bertrand JR, Vasseur JJ, Dupouy C, Debart F.
Gauthier F, et al.
Molecules. 2020 Jun 11;25(11):2714. doi: 10.3390/molecules25112714.
Molecules. 2020.
PMID: 32545345
Free PMC article.
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Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2'-position.
Gauthier F, Claveau S, Bertrand JR, Vasseur JJ, Dupouy C, Debart F.
Gauthier F, et al.
Bioorg Med Chem. 2018 Sep 1;26(16):4635-4643. doi: 10.1016/j.bmc.2018.07.033. Epub 2018 Jul 27.
Bioorg Med Chem. 2018.
PMID: 30121212
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