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Page 1
Synthesis and Antimycobacterial Activity of 3-Phenyl-1H-indoles.
Jardim Etchart R, Rambo RS, Lopes Abbadi B, Sperotto N, Ev Neves C, Fries Silva F, Dornelles M, Duarte L, Souza Macchi F, Alberton Perelló M, Vescia Lourega R, Valim Bizarro C, Basso LA, Machado P. Jardim Etchart R, et al. Among authors: souza macchi f. Molecules. 2021 Aug 25;26(17):5148. doi: 10.3390/molecules26175148. Molecules. 2021. PMID: 34500579 Free PMC article.
8-Mercaptoguanine-based inhibitors of Mycobacterium tuberculosis dihydroneopterin aldolase: synthesis, in vitro inhibition and docking studies.
Czeczot AM, Roth CD, Ducati RG, Pissinate K, Rambo RS, Timmers LFSM, Abbadi BL, Macchi FS, Pestana VZ, Basso LA, Machado P, Bizarro CV. Czeczot AM, et al. Among authors: macchi fs. J Enzyme Inhib Med Chem. 2021 Dec;36(1):847-855. doi: 10.1080/14756366.2021.1900157. J Enzyme Inhib Med Chem. 2021. PMID: 33752554 Free PMC article.
1H-Benzo[d]imidazoles and 3,4-dihydroquinazolin-4-ones: Design, synthesis and antitubercular activity.
Macchi FS, Pissinate K, Villela AD, Abbadi BL, Rodrigues-Junior V, Nabinger DD, Altenhofen S, Sperotto N, da Silva Dadda A, Subtil FT, de Freitas TF, Erhart Rauber AP, Borsoi AF, Bonan CD, Bizarro CV, Basso LA, Santos DS, Machado P. Macchi FS, et al. Eur J Med Chem. 2018 Jul 15;155:153-164. doi: 10.1016/j.ejmech.2018.06.005. Epub 2018 Jun 2. Eur J Med Chem. 2018. PMID: 29885576
Pentacyanoferrate(II) complex of pyridine-4- and pyrazine-2-hydroxamic acid as source of HNO: investigation of anti-tubercular and vasodilation activities.
Carvalho EM, de Freitas Paulo T, Saquet AS, Abbadi BL, Macchi FS, Bizarro CV, de Morais Campos R, Ferreira TLA, do Nascimento NRF, Lopes LGF, Chauvin R, Sousa EHS, Bernardes-Génisson V. Carvalho EM, et al. Among authors: macchi fs. J Biol Inorg Chem. 2020 Sep;25(6):887-901. doi: 10.1007/s00775-020-01805-z. Epub 2020 Jul 29. J Biol Inorg Chem. 2020. PMID: 32728907
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
de Moura Sperotto ND, Deves Roth C, Rodrigues-Junior VS, Ev Neves C, Reisdorfer Paula F, da Silva Dadda A, Bergo P, Freitas de Freitas T, Souza Macchi F, Moura S, Duarte de Souza AP, Campos MM, Valim Bizarro C, Santos DS, Basso LA, Machado P. de Moura Sperotto ND, et al. Among authors: souza macchi f. J Med Chem. 2019 Feb 14;62(3):1231-1245. doi: 10.1021/acs.jmedchem.8b01305. Epub 2019 Jan 17. J Med Chem. 2019. PMID: 30615449
Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.
Laborde J, Deraeve C, de Mesquita Vieira FG, Sournia-Saquet A, Rechignat L, Villela AD, Abbadi BL, Macchi FS, Pissinate K, Bizarro CV, Machado P, Basso LA, Pratviel G, de França Lopes LG, Sousa EHS, Bernardes-Génisson V. Laborde J, et al. Among authors: macchi fs. J Inorg Biochem. 2018 Feb;179:71-81. doi: 10.1016/j.jinorgbio.2017.11.013. Epub 2017 Nov 21. J Inorg Biochem. 2018. PMID: 29175704