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Mitochondrial AKAP1 supports mTOR pathway and tumor growth.
Rinaldi L, Sepe M, Delle Donne R, Conte K, Arcella A, Borzacchiello D, Amente S, De Vita F, Porpora M, Garbi C, Oliva MA, Procaccini C, Faicchia D, Matarese G, Zito Marino F, Rocco G, Pignatiello S, Franco R, Insabato L, Majello B, Feliciello A. Rinaldi L, et al. Among authors: de vita f. Cell Death Dis. 2017 Jun 1;8(6):e2842. doi: 10.1038/cddis.2017.241. Cell Death Dis. 2017. PMID: 28569781 Free PMC article.
Mutant AKT1-E17K is oncogenic in lung epithelial cells.
De Marco C, Malanga D, Rinaldo N, De Vita F, Scrima M, Lovisa S, Fabris L, Carriero MV, Franco R, Rizzuto A, Baldassarre G, Viglietto G. De Marco C, et al. Among authors: de vita f. Oncotarget. 2015 Nov 24;6(37):39634-50. doi: 10.18632/oncotarget.4022. Oncotarget. 2015. PMID: 26053093 Free PMC article.
The T197A Knock-in Model of Cdkn1b Gene to Study the Effects of p27 Restoration In Vivo.
De Marco C, Rinaldo N, De Vita F, Forzati F, Caira E, Iovane V, Paciello O, Montanaro D, D'Andrea S, Baldassarre G, Papparella S, Malanga D, Baldi A, Viglietto G. De Marco C, et al. Among authors: de vita f. Mol Cancer Ther. 2019 Feb;18(2):482-493. doi: 10.1158/1535-7163.MCT-18-0134. Epub 2018 Nov 13. Mol Cancer Ther. 2019. PMID: 30425132