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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.
Wienke J, Visser LL, Kholosy WM, Keller KM, Barisa M, Poon E, Munnings-Tomes S, Himsworth C, Calton E, Rodriguez A, Bernardi R, van den Ham F, van Hooff SR, Matser YAH, Tas ML, Langenberg KPS, Lijnzaad P, Borst AL, Zappa E, Bergsma FJ, Strijker JGM, Verhoeven BM, Mei S, Kramdi A, Restuadi R, Sanchez-Bernabeu A, Cornel AM, Holstege FCP, Gray JC, Tytgat GAM, Scheijde-Vermeulen MA, Wijnen MHWA, Dierselhuis MP, Straathof K, Behjati S, Wu W, Heck AJR, Koster J, Nierkens S, Janoueix-Lerosey I, de Krijger RR, Baryawno N, Chesler L, Anderson J, Caron HN, Margaritis T, van Noesel MM, Molenaar JJ. Wienke J, et al. Among authors: van den ham f. Cancer Cell. 2024 Feb 12;42(2):283-300.e8. doi: 10.1016/j.ccell.2023.12.008. Epub 2024 Jan 4. Cancer Cell. 2024. PMID: 38181797 Free PMC article.
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Cornel AM, Dunnebach E, Hofman DA, Das S, Sengupta S, van den Ham F, Wienke J, Strijker JGM, van den Beemt DAMH, Essing AHW, Koopmans B, Engels SAG, Lo Presti V, Szanto CS, George RE, Molenaar JJ, van Heesch S, Dierselhuis MP, Nierkens S. Cornel AM, et al. Among authors: van den ham f. J Immunother Cancer. 2022 Dec;10(12):e005002. doi: 10.1136/jitc-2022-005002. J Immunother Cancer. 2022. PMID: 36521927 Free PMC article.
Neuroblastoma and DIPG Organoid Coculture System for Personalized Assessment of Novel Anticancer Immunotherapies.
M Kholosy W, Derieppe M, van den Ham F, Ober K, Su Y, Custers L, Schild L, M J van Zogchel L, M Wellens L, R Ariese H, Szanto CL, Wienke J, Dierselhuis MP, van Vuurden D, Dolman EM, Molenaar JJ. M Kholosy W, et al. Among authors: van den ham f. J Pers Med. 2021 Aug 30;11(9):869. doi: 10.3390/jpm11090869. J Pers Med. 2021. PMID: 34575646 Free PMC article.