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Page 1
Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry.
Anal Chem. 2023 Jan 31;95(4):2203-2212. doi: 10.1021/acs.analchem.2c03099. Epub 2023 Jan 20.
Anal Chem. 2023.
PMID: 36669833
Free PMC article.
Multiattribute Monitoring of Antibody Charge Variants by Cation-Exchange Chromatography Coupled to Native Mass Spectrometry.
Haberger M, Heidenreich AK, Hook M, Fichtl J, Lang R, Cymer F, Adibzadeh M, Kuhne F, Wegele H, Reusch D, Bonnington L, Bulau P.
Haberger M, et al. Among authors: kuhne f.
J Am Soc Mass Spectrom. 2021 Aug 4;32(8):2062-2071. doi: 10.1021/jasms.0c00446. Epub 2021 Mar 9.
J Am Soc Mass Spectrom. 2021.
PMID: 33687195
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The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange.
Kuhne F, Bonnington L, Malik S, Thomann M, Avenal C, Cymer F, Wegele H, Reusch D, Mormann M, Bulau P.
Kuhne F, et al.
Antibodies (Basel). 2019 Oct 1;8(4):49. doi: 10.3390/antib8040049.
Antibodies (Basel). 2019.
PMID: 31581521
Free PMC article.
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Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix.
Högel P, Götz A, Kuhne F, Ebert M, Stelzer W, Rand KD, Scharnagl C, Langosch D.
Högel P, et al. Among authors: kuhne f.
Biochemistry. 2018 Feb 27;57(8):1326-1337. doi: 10.1021/acs.biochem.7b01197. Epub 2018 Feb 9.
Biochemistry. 2018.
PMID: 29389107
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Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting.
Thomann M, Malik S, Kuhne F, Avenal C, Plath F, Bonnington L, Reusch D, Bulau P, Cymer F.
Thomann M, et al. Among authors: kuhne f.
Bioanalysis. 2019 Aug;11(15):1437-1449. doi: 10.4155/bio-2019-0124.
Bioanalysis. 2019.
PMID: 31490109
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Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes.
Lippold S, Mistry K, Lenka S, Whang K, Liu P, Pitschi S, Kuhne F, Reusch D, Cadang L, Knaupp A, Izadi S, Dunkle A, Yang F, Schlothauer T.
Lippold S, et al. Among authors: kuhne f.
Front Immunol. 2023 Sep 18;14:1260446. doi: 10.3389/fimmu.2023.1260446. eCollection 2023.
Front Immunol. 2023.
PMID: 37790943
Free PMC article.
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