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Conformational stability of SARS-CoV-2 glycoprotein spike variants.
Arruda HRS, Lima TM, Alvim RGF, Victorio FBA, Abreu DPB, Marsili FF, Cruz KD, Marques MA, Sosa-Acosta P, Quinones-Vega M, de S Guedes J, Nogueira FCS, Silva JL, Castilho LR, de Oliveira GAP. Arruda HRS, et al. Among authors: marsili ff. iScience. 2023 Jan 20;26(1):105696. doi: 10.1016/j.isci.2022.105696. Epub 2022 Nov 30. iScience. 2023. PMID: 36465857 Free PMC article.
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum.
Dos-Santos JS, Firmino-Cruz L, da Fonseca-Martins AM, Oliveira-Maciel D, Perez GG, Roncaglia-Pereira VA, Dumard CH, Guedes-da-Silva FH, Santos ACV, Leandro MDS, Ferreira JRM, Guimarães-Pinto K, Conde L, Rodrigues DAS, Silva MVM, Alvim RGF, Lima TM, Marsili FF, Abreu DPB, Ferreira OC Jr, Mohana Borges RDS, Tanuri A, Souza TML, Rossi-Bergmann B, Vale AM, Silva JL, de Oliveira AC, Filardy AD, Gomes AMO, de Matos Guedes HL. Dos-Santos JS, et al. Among authors: marsili ff. Front Immunol. 2022 Jun 30;13:884760. doi: 10.3389/fimmu.2022.884760. eCollection 2022. Front Immunol. 2022. PMID: 35844561 Free PMC article.
Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency.
Cunha LER, Stolet AA, Strauch MA, Pereira VAR, Dumard CH, Gomes AMO, Monteiro FL, Higa LM, Souza PNC, Fonseca JG, Pontes FE, Meirelles LGR, Albuquerque JWM, Sacramento CQ, Fintelman-Rodrigues N, Lima TM, Alvim RGF, Marsili FF, Caldeira MM, Zingali RB, de Oliveira GAP, Souza TML, Silva AS, Muller R, Rodrigues DDRF, Jesus da Costa L, Alves ADR, Pinto MA, Oliveira AC, Guedes HLM, Tanuri A, Castilho LR, Silva JL. Cunha LER, et al. Among authors: marsili ff. iScience. 2021 Nov 19;24(11):103315. doi: 10.1016/j.isci.2021.103315. Epub 2021 Oct 23. iScience. 2021. PMID: 34723156 Free PMC article.
Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice.
Firmino-Cruz L, Dos-Santos JS, da Fonseca-Martins AM, Oliveira-Maciel D, Guadagnini-Perez G, Roncaglia-Pereira VA, Dumard CH, Guedes-da-Silva FH, Vicente Santos AC, Alvim RGF, Lima TM, Marsili FF, Abreu DPB, Rossi-Bergmann B, Vale AM, Filardy AD, Silva JL, de Oliveira AC, Gomes AMO, de Matos Guedes HL. Firmino-Cruz L, et al. Among authors: marsili ff. Vaccines (Basel). 2022 Aug 12;10(8):1305. doi: 10.3390/vaccines10081305. Vaccines (Basel). 2022. PMID: 36016193 Free PMC article.
From a recombinant key antigen to an accurate, affordable serological test: Lessons learnt from COVID-19 for future pandemics.
Alvim RGF, Lima TM, Rodrigues DAS, Marsili FF, Bozza VBT, Higa LM, Monteiro FL, Abreu DPB, Leitão IC, Carvalho RS, Galliez RM, Castineiras TMPP, Travassos LH, Nobrega A, Tanuri A, Ferreira OC Jr, Vale AM, Castilho LR. Alvim RGF, et al. Among authors: marsili ff. Biochem Eng J. 2022 Aug;186:108537. doi: 10.1016/j.bej.2022.108537. Epub 2022 Jul 16. Biochem Eng J. 2022. PMID: 35874089 Free PMC article.