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Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
Petukhova VZ, Aboagye SY, Ardini M, Lullo RP, Fata F, Byrne ME, Gabriele F, Martin LM, Harding LNM, Gone V, Dangi B, Lantvit DD, Nikolic D, Ippoliti R, Effantin G, Ling WL, Johnson JJ, Thatcher GRJ, Angelucci F, Williams DL, Petukhov PA. Petukhova VZ, et al. Among authors: gabriele f. Nat Commun. 2023 Jun 22;14(1):3737. doi: 10.1038/s41467-023-39444-y. Nat Commun. 2023. PMID: 37349300 Free PMC article.
Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus.
Fata F, Gencheva R, Cheng Q, Lullo R, Ardini M, Silvestri I, Gabriele F, Ippoliti R, Bulman CA, Sakanari JA, Williams DL, Arnér ESJ, Angelucci F. Fata F, et al. Among authors: gabriele f. Redox Biol. 2022 May;51:102278. doi: 10.1016/j.redox.2022.102278. Epub 2022 Mar 4. Redox Biol. 2022. PMID: 35276442 Free PMC article.
Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.
Pedersen MF, Wróbel TM, Märcher-Rørsted E, Pedersen DS, Møller TC, Gabriele F, Pedersen H, Matosiuk D, Foster SR, Bouvier M, Bräuner-Osborne H. Pedersen MF, et al. Among authors: gabriele f. Neuropharmacology. 2020 Apr;166:107718. doi: 10.1016/j.neuropharm.2019.107718. Epub 2019 Jul 24. Neuropharmacology. 2020. PMID: 31351108 Free article.