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Page 1
A Systematic Approach to the Discovery of Protein-Protein Interaction Stabilizers.
Kenanova DN, Visser EJ, Virta JM, Sijbesma E, Centorrino F, Vickery HR, Zhong M, Neitz RJ, Brunsveld L, Ottmann C, Arkin MR. Kenanova DN, et al. Among authors: centorrino f. ACS Cent Sci. 2023 Apr 18;9(5):937-946. doi: 10.1021/acscentsci.2c01449. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252362 Free PMC article.
14-3-3: A Case Study in PPI Modulation.
Ballone A, Centorrino F, Ottmann C. Ballone A, et al. Among authors: centorrino f. Molecules. 2018 Jun 8;23(6):1386. doi: 10.3390/molecules23061386. Molecules. 2018. PMID: 29890630 Free PMC article. Review.
IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Andlovic B, Heilmann G, Ninck S, Andrei SA, Centorrino F, Higuchi Y, Kato N, Brunsveld L, Arkin M, Menninger S, Choidas A, Wolf A, Klebl B, Kaschani F, Kaiser M, Eickhoff J, Ottmann C. Andlovic B, et al. Among authors: centorrino f. Cell Chem Biol. 2023 Jun 15;30(6):573-590.e6. doi: 10.1016/j.chembiol.2023.04.005. Epub 2023 May 1. Cell Chem Biol. 2023. PMID: 37130519
Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Centorrino F, Andlovic B, Cossar P, Brunsveld L, Ottmann C. Centorrino F, et al. Curr Res Struct Biol. 2021 Dec 29;4:21-28. doi: 10.1016/j.crstbi.2021.12.003. eCollection 2022. Curr Res Struct Biol. 2021. PMID: 35036934 Free PMC article.
Interaction of an IκBα Peptide with 14-3-3.
Wolter M, Santo DL, Herman P, Ballone A, Centorrino F, Obsil T, Ottmann C. Wolter M, et al. Among authors: centorrino f. ACS Omega. 2020 Mar 6;5(10):5380-5388. doi: 10.1021/acsomega.9b04413. eCollection 2020 Mar 17. ACS Omega. 2020. PMID: 32201828 Free PMC article.
Protein X-ray crystallography of the 14-3-3ζ/SOS1 complex.
Ballone A, Centorrino F, Wolter M, Ottmann C. Ballone A, et al. Among authors: centorrino f. Data Brief. 2018 Jun 28;19:1683-1687. doi: 10.1016/j.dib.2018.06.060. eCollection 2018 Aug. Data Brief. 2018. PMID: 30229043 Free PMC article.
Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3.
Brink HJ, van Senten JR, De Vries-van Leeuwen IJ, da Costa Pereira D, Piersma SR, Jimenez CR, Centorrino F, Ottmann C, Siderius M, Smit MJ, de Boer AH. Brink HJ, et al. Among authors: centorrino f. ACS Chem Biol. 2022 Nov 18;17(11):2972-2978. doi: 10.1021/acschembio.2c00299. Epub 2022 Oct 18. ACS Chem Biol. 2022. PMID: 36255265 Free PMC article.