Transient Activations of Rac1 at the Lamellipodium Tip Trigger Membrane Protrusion.
Mehidi A, Rossier O, Schaks M, Chazeau A, Binamé F, Remorino A, Coppey M, Karatas Z, Sibarita JB, Rottner K, Moreau V, Giannone G.
Mehidi A, et al.
Curr Biol. 2019 Sep 9;29(17):2852-2866.e5. doi: 10.1016/j.cub.2019.07.035. Epub 2019 Aug 15.
Curr Biol. 2019.
PMID: 31422887
Free article.
The spatiotemporal coordination of actin regulators in the lamellipodium determines the dynamics and architecture of branched F-actin networks during cell migration. The WAVE regulatory complex (WRC), an effector of Rac1 during cell protrusion, is concentrated at the lamel …
The spatiotemporal coordination of actin regulators in the lamellipodium determines the dynamics and architecture of branched F-actin …