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Page 1
Natural products in drug discovery: advances and opportunities.
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Atanasov AG, et al. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z. Epub 2021 Jan 28. Nat Rev Drug Discov. 2021. PMID: 33510482 Free PMC article. Review.
Auger Shake-Up Assisted Electron Recapture.
Žitnik M, Hrast M, Mihelič A, Bučar K, Turnšek J, Püttner R, Goldsztejn G, Marchenko T, Guillemin R, Journel L, Travnikova O, Ismail I, Piancastelli MN, Simon M, Ceolin D, Kavčič M. Žitnik M, et al. Phys Rev Lett. 2023 Nov 17;131(20):203001. doi: 10.1103/PhysRevLett.131.203001. Phys Rev Lett. 2023. PMID: 38039460
Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents.
Kalt MM, Schuehly W, Saf R, Ochensberger S, Solnier J, Bucar F, Kaiser M, Presser A. Kalt MM, et al. Eur J Med Chem. 2020 Dec 1;207:112837. doi: 10.1016/j.ejmech.2020.112837. Epub 2020 Sep 12. Eur J Med Chem. 2020. PMID: 33002847 Free article.
Antiprotozoal activity was assessed against Plasmodium falciparum (P.f.) NF54 and Trypanosoma brucei rhodesiense (T.b.r.) STIB900, and antimycobacterial activity against Mycobacterium smegmatis (M.s.) mc(2) 155. ...
Antiprotozoal activity was assessed against Plasmodium falciparum (P.f.) NF54 and Trypanosoma brucei rhodesiense (T.b.r.) STIB900, an …
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
Schumacher MA, Hsieh JJ, Liu CY, Appel KL, Waddell A, Almohazey D, Katada K, Bernard JK, Bucar EB, Gadeock S, Maselli KM, Washington MK, Grikscheit TC, Warburton D, Rosen MJ, Frey MR. Schumacher MA, et al. Nat Commun. 2021 Feb 5;12(1):836. doi: 10.1038/s41467-021-21113-7. Nat Commun. 2021. PMID: 33547321 Free PMC article.
Sprouty2 is downregulated by acute inflammation; this appears to be a protective response, as VillinCre;Sprouty2(F/F) mice are resistant to DSS colitis. In contrast, Sprouty2 is elevated in chronic colitis and in colons of inflammatory bowel disease patients, sugges …
Sprouty2 is downregulated by acute inflammation; this appears to be a protective response, as VillinCre;Sprouty2(F/F) mice are …
A modified magnetic bottle electron spectrometer for the detection of multiply charged ions in coincidence with all correlated electrons: decay pathways to Xe3+ above xenon-4d ionization threshold.
Ismail I, Khalal MA, Huttula M, Jänkälä K, Bizau JM, Cubaynes D, Hikosaka Y, Bučar K, Žitnik M, Andric L, Lablanquie P, Palaudoux J, Penent F. Ismail I, et al. Phys Chem Chem Phys. 2022 Aug 31;24(34):20219-20227. doi: 10.1039/d2cp02930h. Phys Chem Chem Phys. 2022. PMID: 35983783
In vitro 12(S)-HETE inhibitory activities of naphthoquinones isolated from the root bark of Euclea racemosa ssp. schimperi.
Wube AA, Streit B, Gibbons S, Asres K, Bucar F. Wube AA, et al. J Ethnopharmacol. 2005 Nov 14;102(2):191-6. doi: 10.1016/j.jep.2005.06.009. Epub 2005 Jul 12. J Ethnopharmacol. 2005. PMID: 16019177
The extracts of Euclea racemosa Murr. ssp. schimperi (A. DC.) F. White (Ebenaceae) obtained by maceration and naphthoquinones isolated from the dichloromethane extract have been investigated for their 12(S)-HETE inhibitory activity using human platelets. ...
The extracts of Euclea racemosa Murr. ssp. schimperi (A. DC.) F. White (Ebenaceae) obtained by maceration and naphthoquinones isolate …
15 results