The objective of this study was to evaluate the urinary iodine concentration in Gorgan located in northern Iran, which is a cosmopolitan society and on the basis of such determination the endemic goiter in the region could be estimated. The sample population were a total of 287 people (23.3% male, 76.7% female) referred to Danesh Medical Diagnostic Laboratory for the urinary iodine measurement, during 2004-05. Urinary iodine level was determined using acid digestion method. The results from this study indicated that 2.1, 3.8 and 9.8% of sample population had urinary iodine level of <2, 2-4.9 and 5-9.9 microg dL(-1), respectively which are defined as sever, moderate and mild iodine deficiency. Therefore 45 (15.7%) of the sample population in this study could be assessed for goiter prevalence, the mean differences of iodine concentration in male and female subjects were not significant. In conclusion, low urinary iodine of <10 microg dL(-1) concentration may help to give a direction for a further examination in the thyroid gland abnormalities.