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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 6
2003 7
2004 5
2005 7
2006 8
2007 4
2008 5
2009 8
2010 7
2011 8
2012 6
2013 7
2014 12
2015 6
2016 11
2017 12
2018 14
2019 9
2020 11
2021 9
2022 9
2023 7
2024 3

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162 results

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Page 1
How Carvedilol activates β2-adrenoceptors.
Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim VJY, Matthees ESF, Drube J, Miess-Tanneberg E, Malan D, Szpakowska M, Monteleone S, Grimes J, Koszegi Z, Lanoiselée Y, O'Brien S, Pavlaki N, Dobberstein N, Inoue A, Nikolaev V, Calebiro D, Chevigné A, Sasse P, Schulz S, Hoffmann C, Kolb P, Waldhoer M, Simon K, Gomeza J, Kostenis E. Benkel T, et al. Among authors: kostenis e. Nat Commun. 2022 Nov 19;13(1):7109. doi: 10.1038/s41467-022-34765-w. Nat Commun. 2022. PMID: 36402762 Free PMC article.
The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.
Klose CSN, Mahlakõiv T, Moeller JB, Rankin LC, Flamar AL, Kabata H, Monticelli LA, Moriyama S, Putzel GG, Rakhilin N, Shen X, Kostenis E, König GM, Senda T, Carpenter D, Farber DL, Artis D. Klose CSN, et al. Among authors: kostenis e. Nature. 2017 Sep 14;549(7671):282-286. doi: 10.1038/nature23676. Epub 2017 Sep 6. Nature. 2017. PMID: 28869965 Free PMC article.
Community guidelines for GPCR ligand bias: IUPHAR review 32.
Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov KA, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, Shukla AK, Sommer ME, Gloriam DE. Kolb P, et al. Among authors: kostenis e. Br J Pharmacol. 2022 Jul;179(14):3651-3674. doi: 10.1111/bph.15811. Epub 2022 Mar 27. Br J Pharmacol. 2022. PMID: 35106752 Free PMC article. Review.
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.
Lorza-Gil E, Kaiser G, Carlein C, Hoffmann MDA, König GM, Haug S, Prates Roma L, Rexen Ulven E, Ulven T, Kostenis E, Birkenfeld AL, Häring HU, Ullrich S, Gerst F. Lorza-Gil E, et al. Among authors: kostenis e. Diabetologia. 2023 Aug;66(8):1501-1515. doi: 10.1007/s00125-023-05932-5. Epub 2023 May 23. Diabetologia. 2023. PMID: 37217659 Free PMC article.
Heterotrimeric Gq proteins as therapeutic targets?
Kostenis E, Pfeil EM, Annala S. Kostenis E, et al. J Biol Chem. 2020 Apr 17;295(16):5206-5215. doi: 10.1074/jbc.REV119.007061. Epub 2020 Mar 2. J Biol Chem. 2020. PMID: 32122969 Free PMC article. Review.
Temporal Bias: Time-Encoded Dynamic GPCR Signaling.
Grundmann M, Kostenis E. Grundmann M, et al. Among authors: kostenis e. Trends Pharmacol Sci. 2017 Dec;38(12):1110-1124. doi: 10.1016/j.tips.2017.09.004. Epub 2017 Oct 23. Trends Pharmacol Sci. 2017. PMID: 29074251 Review.
Giving ERK a jERK from the endosome.
Kostenis E, Bravo S, Gomeza J. Kostenis E, et al. Trends Pharmacol Sci. 2023 Mar;44(3):131-133. doi: 10.1016/j.tips.2022.12.004. Epub 2023 Jan 3. Trends Pharmacol Sci. 2023. PMID: 36604224
162 results