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The VRK1 chromatin kinase regulates the acetyltransferase activity of Tip60/KAT5 by sequential phosphorylations in response to DNA damage.
García-González R, Monte-Serrano E, Morejón-García P, Navarro-Carrasco E, Lazo PA. García-González R, et al. Among authors: monte serrano e. Biochim Biophys Acta Gene Regul Mech. 2022 Nov;1865(8):194887. doi: 10.1016/j.bbagrm.2022.194887. Epub 2022 Oct 21. Biochim Biophys Acta Gene Regul Mech. 2022. PMID: 36280132 Free article.
Loss of VRK1 alters the nuclear phosphoproteome in the DNA damage response to doxorubicin.
Navarro-Carrasco E, Campos-Díaz A, Monte-Serrano E, Rolfs F, de Goeij-de Haas R, Pham TV, Piersma SR, Jiménez CR, Lazo PA. Navarro-Carrasco E, et al. Among authors: monte serrano e. Chem Biol Interact. 2024 Mar 1;391:110908. doi: 10.1016/j.cbi.2024.110908. Epub 2024 Feb 15. Chem Biol Interact. 2024. PMID: 38367682 Free article.
VRK1 Regulates Sensitivity to Oxidative Stress by Altering Histone Epigenetic Modifications and the Nuclear Phosphoproteome in Tumor Cells.
Navarro-Carrasco E, Monte-Serrano E, Campos-Díaz A, Rolfs F, de Goeij-de Haas R, Pham TV, Piersma SR, González-Alonso P, Jiménez CR, Lazo PA. Navarro-Carrasco E, et al. Among authors: monte serrano e. Int J Mol Sci. 2024 Apr 30;25(9):4874. doi: 10.3390/ijms25094874. Int J Mol Sci. 2024. PMID: 38732093 Free PMC article.