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Page 1
Showing results for ester reynolds
Search for Esther Reynolds instead (3 results)
Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial.
Chambers ES, Byrne CS, Morrison DJ, Murphy KG, Preston T, Tedford C, Garcia-Perez I, Fountana S, Serrano-Contreras JI, Holmes E, Reynolds CJ, Roberts JF, Boyton RJ, Altmann DM, McDonald JAK, Marchesi JR, Akbar AN, Riddell NE, Wallis GA, Frost GS. Chambers ES, et al. Gut. 2019 Aug;68(8):1430-1438. doi: 10.1136/gutjnl-2019-318424. Epub 2019 Apr 10. Gut. 2019. PMID: 30971437 Free PMC article. Clinical Trial.
DESIGN: Twelve non-diabetic adults with overweight and obesity received 20 g/day of inulin-propionate ester (IPE), designed to selectively deliver propionate to the colon, a high-fermentable fibre control (inulin) and a low-fermentable fibre control (cellulose) in a random …
DESIGN: Twelve non-diabetic adults with overweight and obesity received 20 g/day of inulin-propionate ester (IPE), designed to select …
Cholesteryl ester storage disease: a rare and possibly treatable cause of premature vascular disease and cirrhosis.
Reynolds T. Reynolds T. J Clin Pathol. 2013 Nov;66(11):918-23. doi: 10.1136/jclinpath-2012-201302. Epub 2013 Sep 2. J Clin Pathol. 2013. PMID: 23999269 Review.
Cholesteryl ester storage disease (CESD) is an autosomal recessive lysosomal storage disorder caused by a variety of mutations of the LIPA gene. These cause reduced activity of lysosomal acid lipase, which results in accumulation of cholesteryl esters in lysosomes. …
Cholesteryl ester storage disease (CESD) is an autosomal recessive lysosomal storage disorder caused by a variety of mutations of the …
An update on trials of novel lipid-lowering drugs.
Wierzbicki AS, Reynolds TM, Viljoen A. Wierzbicki AS, et al. Curr Opin Cardiol. 2018 Jul;33(4):416-422. doi: 10.1097/HCO.0000000000000518. Curr Opin Cardiol. 2018. PMID: 29561321 Review.
A CVD outcome trial in patients with acute coronary syndromes with evolocumab achieved a LDL-C of 0.8 mmol/l (31 mg/dl) and a 20% relative risk reduction in CVD events in 2.2 years. Cholesterol ester transfer protein inhibitors raise high-density lipoprotein cholesterol an …
A CVD outcome trial in patients with acute coronary syndromes with evolocumab achieved a LDL-C of 0.8 mmol/l (31 mg/dl) and a 20% relative r …
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease.
HPS3/TIMI55–REVEAL Collaborative Group; Bowman L, Hopewell JC, Chen F, Wallendszus K, Stevens W, Collins R, Wiviott SD, Cannon CP, Braunwald E, Sammons E, Landray MJ. HPS3/TIMI55–REVEAL Collaborative Group, et al. N Engl J Med. 2017 Sep 28;377(13):1217-1227. doi: 10.1056/NEJMoa1706444. Epub 2017 Aug 28. N Engl J Med. 2017. PMID: 28847206 Free article. Clinical Trial.
BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib …
BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based trea …
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation.
Speer NO, Braun RJ, Reynolds EG, Brudnicka A, Swanson JMJ, Henne WM. Speer NO, et al. J Cell Biol. 2024 Jan 1;223(1):e202303026. doi: 10.1083/jcb.202303026. Epub 2023 Oct 27. J Cell Biol. 2024. PMID: 37889293 Free PMC article.
Cells store lipids in the form of triglyceride (TG) and sterol ester (SE) in lipid droplets (LDs). Distinct pools of LDs exist, but a pervasive question is how proteins localize to and convey functions to LD subsets. ...
Cells store lipids in the form of triglyceride (TG) and sterol ester (SE) in lipid droplets (LDs). Distinct pools of LDs exist, but a …
Dehydroalkylative Activation of CNN- and PNN-Pincer Ruthenium Catalysts for Ester Hydrogenation.
He T, Buttner JC, Reynolds EF, Pham J, Malek JC, Keith JM, Chianese AR. He T, et al. J Am Chem Soc. 2019 Oct 30;141(43):17404-17413. doi: 10.1021/jacs.9b09326. Epub 2019 Oct 17. J Am Chem Soc. 2019. PMID: 31589441
A new PNN-pincer ruthenium(0)-imine complex is a highly active catalyst for ester hydrogenation at room temperature, giving up to 15 500 turnovers with no added base. ...These observations have potentially broad implications for the identities of catalytic intermediates in …
A new PNN-pincer ruthenium(0)-imine complex is a highly active catalyst for ester hydrogenation at room temperature, giving up to 15 …
The key role of the latent N-H group in Milstein's catalyst for ester hydrogenation.
Pham J, Jarczyk CE, Reynolds EF, Kelly SE, Kim T, He T, Keith JM, Chianese AR. Pham J, et al. Chem Sci. 2021 May 24;12(24):8477-8492. doi: 10.1039/d1sc00703c. eCollection 2021 Jun 23. Chem Sci. 2021. PMID: 35355805 Free PMC article.
Our DFT analysis shows that the minimum-energy pathways for hydrogen activation, ester hydrogenolysis, and aldehyde hydrogenation rely on the key involvement of the nascent N-H group. We have isolated and crystallographically characterized two catalytic intermediates, a ru …
Our DFT analysis shows that the minimum-energy pathways for hydrogen activation, ester hydrogenolysis, and aldehyde hydrogenation rel …
Using Carboxy Fluorescein Succinimidyl Ester (CFSE) to Identify Quiescent Glioblastoma Stem-Like Cells.
Azari H, Deleyrolle LP, Reynolds BA. Azari H, et al. Methods Mol Biol. 2018;1686:59-67. doi: 10.1007/978-1-4939-7371-2_4. Methods Mol Biol. 2018. PMID: 29030812
In this chapter, we describe detailed technical procedures for the isolation of quiescent or infrequently dividing stem-like cells in cultured glioblastoma tumor cells using carboxy fluorescein succinimidyl ester (CFSE) staining and flow cytometric analysis. Quiescent glio …
In this chapter, we describe detailed technical procedures for the isolation of quiescent or infrequently dividing stem-like cells in cultur …
Decarboxylative N-Alkylation of Azoles through Visible-Light-Mediated Organophotoredox Catalysis.
Kobayashi R, Shibutani S, Nagao K, Ikeda Z, Wang J, Ibáñez I, Reynolds M, Sasaki Y, Ohmiya H. Kobayashi R, et al. Org Lett. 2021 Jul 16;23(14):5415-5419. doi: 10.1021/acs.orglett.1c01745. Epub 2021 Jun 17. Org Lett. 2021. PMID: 34139122
An organophotoredox-catalyzed decarboxylative cross-coupling between azole nucleophiles and aliphatic carboxylic acid-derived redox-active esters is demonstrated. This protocol efficiently installs various tertiary or secondary alkyl fragments onto the nitrogen atom of azo …
An organophotoredox-catalyzed decarboxylative cross-coupling between azole nucleophiles and aliphatic carboxylic acid-derived redox-active …
167 results