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Page 1
Assessment of the amorphous solid dispersion erosion behavior following a novel small-scale predictive approach.
Eur J Pharm Sci. 2021 Mar 1;158:105682. doi: 10.1016/j.ejps.2020.105682. Epub 2020 Dec 23.
Eur J Pharm Sci. 2021.
PMID: 33347981
Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation.
Bochmann ES, Gryczke A, Wagner KG.
Bochmann ES, et al.
Pharmaceutics. 2018 Aug 18;10(3):132. doi: 10.3390/pharmaceutics10030132.
Pharmaceutics. 2018.
PMID: 30126193
Free PMC article.
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Micro-scale solubility assessments and prediction models for active pharmaceutical ingredients in polymeric matrices.
Bochmann ES, Neumann D, Gryczke A, Wagner KG.
Bochmann ES, et al.
Eur J Pharm Biopharm. 2019 Aug;141:111-120. doi: 10.1016/j.ejpb.2019.05.012. Epub 2019 May 14.
Eur J Pharm Biopharm. 2019.
PMID: 31100430
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Numerical simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt viscosity.
Bochmann ES, Steffens KE, Gryczke A, Wagner KG.
Bochmann ES, et al.
Eur J Pharm Biopharm. 2018 Mar;124:34-42. doi: 10.1016/j.ejpb.2017.12.001. Epub 2017 Dec 6.
Eur J Pharm Biopharm. 2018.
PMID: 29221654
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Holistic QbD approach for hot-melt extrusion process design space evaluation: Linking materials science, experimentation and process modeling.
Evans RC, Bochmann ES, Kyeremateng SO, Gryczke A, Wagner KG.
Evans RC, et al. Among authors: bochmann es.
Eur J Pharm Biopharm. 2019 Aug;141:149-160. doi: 10.1016/j.ejpb.2019.05.021. Epub 2019 May 24.
Eur J Pharm Biopharm. 2019.
PMID: 31132400
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Micro-scale prediction method for API-solubility in polymeric matrices and process model for forming amorphous solid dispersion by hot-melt extrusion.
Bochmann ES, Neumann D, Gryczke A, Wagner KG.
Bochmann ES, et al.
Eur J Pharm Biopharm. 2016 Oct;107:40-8. doi: 10.1016/j.ejpb.2016.06.015. Epub 2016 Jun 25.
Eur J Pharm Biopharm. 2016.
PMID: 27349807
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Predicting melt rheology for hot-melt extrusion by means of a simple Tg-measurement.
Bochmann ES, Üstüner EE, Gryczke A, Wagner KG.
Bochmann ES, et al.
Eur J Pharm Biopharm. 2017 Oct;119:47-55. doi: 10.1016/j.ejpb.2017.05.010. Epub 2017 May 19.
Eur J Pharm Biopharm. 2017.
PMID: 28532677
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