Danshensu methyl ester enhances autophagy to attenuate pulmonary fibrosis by targeting lncIAPF-HuR complex.
Zhu Q, Wang J, Ji Y, Luan J, Yue D, Liu W, Li H, Zhang J, Qu G, Lv C, Song X.
Zhu Q, et al.
Front Pharmacol. 2022 Oct 31;13:1013098. doi: 10.3389/fphar.2022.1013098. eCollection 2022.
Front Pharmacol. 2022.
PMID: 36386240
Free PMC article.
Mechanistically, chromatin immunoprecipitation-PCR, RNA immunoprecipitation, half-life, and other experiments revealed that DME inhibited activating transcription factor 3 expression via TGF-beta1 signal transduction leading to a decrease in lncIAPF transcription and stability. M …
Mechanistically, chromatin immunoprecipitation-PCR, RNA immunoprecipitation, half-life, and other experiments revealed that DME inhibited ac …