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Page 1
Showing results for ester molnar
Search for Estera Molnar instead (1 results)
Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol.
Shugg T, Somberg JC, Molnar J, Overholser BR. Shugg T, et al. JACC Clin Electrophysiol. 2020 Jul;6(7):756-759. doi: 10.1016/j.jacep.2020.05.037. JACC Clin Electrophysiol. 2020. PMID: 32703555 Free article. Review.
The authors developed a novel sotalol analogue, soestalol, with an ester linkage introduced to the molecule to shorten half-life. Their hypothesis was that soestalol, but not the acid metabolite, would inhibit the hERG potassium current. ...
The authors developed a novel sotalol analogue, soestalol, with an ester linkage introduced to the molecule to shorten half-life. The …
The potential contribution of impaired brain glucose metabolism to congenital Zika syndrome.
Gilbert-Jaramillo J, Garcez P, James W, Molnár Z, Clarke K. Gilbert-Jaramillo J, et al. J Anat. 2019 Sep;235(3):468-480. doi: 10.1111/joa.12959. Epub 2019 Feb 21. J Anat. 2019. PMID: 30793304 Free PMC article. Review.
Ketone bodies are non-glycolytic brain fuels that are produced during neonatal life, starvation or fasting, ingestion of high-fat low-carbohydrate diets, and following supplementation with ketone esters. We propose that dietary ketones might alter the course of the disease …
Ketone bodies are non-glycolytic brain fuels that are produced during neonatal life, starvation or fasting, ingestion of high-fat low-carboh …
Biosynthesis of Cytosporones in Leotiomycetous Filamentous Fungi.
Li L, Zhong W, Liu H, Espinosa-Artiles P, Xu YM, Wang C, Verdugo Robles JM, Paz TA, Cascaes Inácio M, Chen F, Xu Y, Gunatilaka AAL, Molnár I. Li L, et al. J Am Chem Soc. 2024 Mar 6;146(9):6189-6198. doi: 10.1021/jacs.3c14066. Epub 2024 Feb 22. J Am Chem Soc. 2024. PMID: 38386630
Thioesterase domain-catalyzed transesterification releases ADA esters, some of which are known Nur77 modulators. Alternatively, hydrolytic release allows C6 hydroxylation by a flavin-dependent monooxygenase, yielding a trihydroxybenzene moiety. ...
Thioesterase domain-catalyzed transesterification releases ADA esters, some of which are known Nur77 modulators. Alternatively, hydro …
Turning Red without Feeling Embarrassed─Xanthenium-Based Photocages for Red-Light-Activated Phototherapeutics.
Egyed A, Németh K, Molnár TÁ, Kállay M, Kele P, Bojtár M. Egyed A, et al. J Am Chem Soc. 2023 Feb 8;145(7):4026-34. doi: 10.1021/jacs.2c11499. Online ahead of print. J Am Chem Soc. 2023. PMID: 36752773 Free PMC article.
Very importantly, these new photocages allow installation of various payloads through ester, carbamate, or carbonate linkages even at the last stage of the synthesis. ...
Very importantly, these new photocages allow installation of various payloads through ester, carbamate, or carbonate linkages even at …
Cutin:cutin-acid endo-transacylase (CCT), a cuticle-remodelling enzyme activity in the plant epidermis.
Xin A, Fei Y, Molnar A, Fry SC. Xin A, et al. Biochem J. 2021 Feb 26;478(4):777-798. doi: 10.1042/BCJ20200835. Biochem J. 2021. PMID: 33511979 Free PMC article.
The cuticle, of which cutin is a major component, protects the plant from biotic and abiotic stresses, and cutin has been postulated to constrain organ expansion. We propose that, to allow cutin restructuring, ester bonds in this net-like polymer can be transiently cleaved …
The cuticle, of which cutin is a major component, protects the plant from biotic and abiotic stresses, and cutin has been postulated to cons …
Chemometrics and genome mining reveal an unprecedented family of sugar acid-containing fungal nonribosomal cyclodepsipeptides.
Wang C, Xiao D, Dun B, Yin M, Tsega AS, Xie L, Li W, Yue Q, Wang S, Gao H, Lin M, Zhang L, Molnár I, Xu Y. Wang C, et al. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2123379119. doi: 10.1073/pnas.2123379119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914151 Free PMC article.
Another source of structural diversity is the variable choice of the nucleophile for intramolecular macrocyclic ester formation during xylomyrocin chain termination. This nucleophile is selected from the multiple available alcohol functionalities of the polyol moiety, reve …
Another source of structural diversity is the variable choice of the nucleophile for intramolecular macrocyclic ester formation durin …
Karavilagenin C derivatives as antimalarials.
Ramalhete C, Lopes D, Molnár J, Mulhovo S, Rosário VE, Ferreira MJ. Ramalhete C, et al. Bioorg Med Chem. 2011 Jan 1;19(1):330-8. doi: 10.1016/j.bmc.2010.11.015. Epub 2010 Nov 11. Bioorg Med Chem. 2011. PMID: 21129980
Compounds 1 and 17 and the acyl derivatives 8-16 along with other five esters (2-6, karavoates A-E), previously prepared from 1, were evaluated for their in vitro antimalarial activity against the chloroquine-sensitive (3D7) and the chloroquine-resistant (Dd2) strains of P …
Compounds 1 and 17 and the acyl derivatives 8-16 along with other five esters (2-6, karavoates A-E), previously prepared from 1, were …
61 results