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Page 1
Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes.
J Biol Chem. 2021 Jan-Jun;296:100056. doi: 10.1074/jbc.RA120.015585. Epub 2020 Nov 24.
J Biol Chem. 2021.
PMID: 33172888
Free PMC article.
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS-1 (832/3) cell glucose-stimulated insulin secretion.
Sandhu HK, Neuman JC, Schaid MD, Davis SE, Connors KM, Challa R, Guthery E, Fenske RJ, Patibandla C, Breyer RM, Kimple ME.
Sandhu HK, et al. Among authors: guthery e.
Pharmacol Res Perspect. 2021 Apr;9(2):e00736. doi: 10.1002/prp2.736.
Pharmacol Res Perspect. 2021.
PMID: 33694300
Free PMC article.
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Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E2 Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes.
Schaid MD, Zhu Y, Richardson NE, Patibandla C, Ong IM, Fenske RJ, Neuman JC, Guthery E, Reuter A, Sandhu HK, Fuller MH, Cox ED, Davis DB, Layden BT, Brasier AR, Lamming DW, Ge Y, Kimple ME.
Schaid MD, et al. Among authors: guthery e.
Metabolites. 2021 Jan 16;11(1):58. doi: 10.3390/metabo11010058.
Metabolites. 2021.
PMID: 33467110
Free PMC article.
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