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p53 is renoprotective after ischemic kidney injury by reducing inflammation.
J Am Soc Nephrol. 2013 Jan;24(1):113-24. doi: 10.1681/ASN.2012050469. Epub 2012 Dec 6.
J Am Soc Nephrol. 2013.
PMID: 23222126
Free PMC article.
The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury.
Dagher PC, Mai EM, Hato T, Lee SY, Anderson MD, Karozos SC, Mang HE, Knipe NL, Plotkin Z, Sutton TA.
Dagher PC, et al. Among authors: mai em.
Am J Physiol Renal Physiol. 2012 Jan 15;302(2):F284-91. doi: 10.1152/ajprenal.00317.2011. Epub 2011 Nov 2.
Am J Physiol Renal Physiol. 2012.
PMID: 22049400
Free PMC article.
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Inhibition of Toll-Like Receptor 4 Signaling Mitigates Microvascular Loss but Not Fibrosis in a Model of Ischemic Acute Kidney Injury.
Dagher PC, Hato T, Mang HE, Plotkin Z, Richardson QV, Massad M, Mai E, Kuehl SE, Graham P, Kumar R, Sutton TA.
Dagher PC, et al. Among authors: mai e.
Int J Mol Sci. 2016 Apr 29;17(5):647. doi: 10.3390/ijms17050647.
Int J Mol Sci. 2016.
PMID: 27136544
Free PMC article.
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