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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2013 2
2015 1
2016 3
2017 4
2018 3
2019 3
2020 6
2021 5
2022 3
2023 3
2024 1

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30 results

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Page 1
OX40L Inhibition Suppresses KLH-driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof-of-Pharmacology for KY1005.
Saghari M, Gal P, Gilbert S, Yateman M, Porter-Brown B, Brennan N, Quaratino S, Wilson R, Grievink HW, Klaassen ES, Bergmann KR, Burggraaf J, van Doorn MBA, Powell J, Moerland M, Rissmann R. Saghari M, et al. Among authors: klaassen es. Clin Pharmacol Ther. 2022 May;111(5):1121-1132. doi: 10.1002/cpt.2539. Epub 2022 Mar 1. Clin Pharmacol Ther. 2022. PMID: 35092305 Free PMC article. Clinical Trial.
Omiganan Enhances Imiquimod-Induced Inflammatory Responses in Skin of Healthy Volunteers.
Niemeyer-van der Kolk T, Assil S, Buters TP, Rijsbergen M, Klaassen ES, Feiss G, Florencia E, Prens EP, Burggraaf J, van Doorn MBA, Rissmann R, Moerland M. Niemeyer-van der Kolk T, et al. Among authors: klaassen es. Clin Transl Sci. 2020 May;13(3):573-579. doi: 10.1111/cts.12741. Epub 2020 Feb 13. Clin Transl Sci. 2020. PMID: 32043302 Free PMC article. Clinical Trial.
First-in-human trial to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of STR-324, a dual enkephalinase inhibitor for pain management.
Moss LM, Berends CL, van Brummelen EMJ, Kamerling IMC, Klaassen ES, Bergmann K, Ville V, Juarez-Perez V, Benichou AC, Groeneveld GJ. Moss LM, et al. Among authors: klaassen es. Br J Clin Pharmacol. 2022 Jan;88(1):103-114. doi: 10.1111/bcp.14931. Epub 2021 Jul 16. Br J Clin Pharmacol. 2022. PMID: 34046921 Free PMC article. Clinical Trial.
Impact of oral administration of single strain Lactococcus lactis spp. cremoris on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers.
Saghari M, Gal P, Grievink HW, Klaassen ES, Itano A, McHale D, Moerland M. Saghari M, et al. Among authors: klaassen es. Front Immunol. 2022 Dec 7;13:1009304. doi: 10.3389/fimmu.2022.1009304. eCollection 2022. Front Immunol. 2022. PMID: 36582231 Free PMC article. Clinical Trial.
Safety, pharmacokinetics and exploratory pro-cognitive effects of HTL0018318, a selective M1 receptor agonist, in healthy younger adult and elderly subjects: a multiple ascending dose study.
Bakker C, Tasker T, Liptrot J, Hart EP, Klaassen ES, Doll RJ, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Cross DM, Groeneveld GJ, Nathan PJ. Bakker C, et al. Among authors: klaassen es. Alzheimers Res Ther. 2021 Apr 21;13(1):87. doi: 10.1186/s13195-021-00816-5. Alzheimers Res Ther. 2021. PMID: 33883008 Free PMC article. Clinical Trial.
First-in-human trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of zagociguat (CY6463), a CNS-penetrant soluble guanylyl cyclase stimulator.
van Kraaij SJW, Gal P, Borghans LGJM, Klaassen ES, Dijkstra F, Winrow C, Glasser C, Groeneveld GJ. van Kraaij SJW, et al. Among authors: klaassen es. Clin Transl Sci. 2023 Aug;16(8):1381-1395. doi: 10.1111/cts.13537. Epub 2023 May 3. Clin Transl Sci. 2023. PMID: 37118895 Free PMC article. Clinical Trial.
Randomized placebo-controlled crossover study to assess tolerability and pharmacodynamics of zagociguat, a soluble guanylyl cyclase stimulator, in healthy elderly.
van Kraaij SJW, Borghans L, Klaassen ES, Gal P, van der Grond J, Tripp K, Winrow C, Glasser C, Groeneveld GJ. van Kraaij SJW, et al. Among authors: klaassen es. Br J Clin Pharmacol. 2023 Dec;89(12):3606-3617. doi: 10.1111/bcp.15861. Epub 2023 Aug 13. Br J Clin Pharmacol. 2023. PMID: 37488930 Clinical Trial.
30 results