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Page 1
New Synthetic Lethality Re-Sensitizing Platinum-Refractory Cancer Cells to Cisplatin In Vitro: The Rationale to Co-Use PARP and ATM Inhibitors.
Int J Mol Sci. 2021 Dec 11;22(24):13324. doi: 10.3390/ijms222413324.
Int J Mol Sci. 2021.
PMID: 34948122
Free PMC article.
Identification of a novel effector domain of BIN1 for cancer suppression.
Lundgaard GL, Daniels NE, Pyndiah S, Cassimere EK, Ahmed KM, Rodrigue A, Kihara D, Post CB, Sakamuro D.
Lundgaard GL, et al. Among authors: cassimere ek.
J Cell Biochem. 2011 Oct;112(10):2992-3001. doi: 10.1002/jcb.23222.
J Cell Biochem. 2011.
PMID: 21678469
Free PMC article.
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Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin.
Folk WP, Kumari A, Iwasaki T, Pyndiah S, Johnson JC, Cassimere EK, Abdulovic-Cui AL, Sakamuro D.
Folk WP, et al. Among authors: cassimere ek.
J Biol Chem. 2019 Apr 5;294(14):5700-5719. doi: 10.1074/jbc.RA118.005699. Epub 2019 Feb 7.
J Biol Chem. 2019.
PMID: 30733337
Free PMC article.
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LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis.
Castle CD, Cassimere EK, Denicourt C.
Castle CD, et al. Among authors: cassimere ek.
Mol Biol Cell. 2012 Feb;23(4):716-28. doi: 10.1091/mbc.E11-06-0530. Epub 2011 Dec 21.
Mol Biol Cell. 2012.
PMID: 22190735
Free PMC article.
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Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis.
Castle CD, Cassimere EK, Lee J, Denicourt C.
Castle CD, et al. Among authors: cassimere ek.
Mol Cell Biol. 2010 Sep;30(18):4404-14. doi: 10.1128/MCB.00358-10. Epub 2010 Jul 20.
Mol Cell Biol. 2010.
PMID: 20647540
Free PMC article.
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p27Kip1 Is Required to Mediate a G1 Cell Cycle Arrest Downstream of ATM following Genotoxic Stress.
Cassimere EK, Mauvais C, Denicourt C.
Cassimere EK, et al.
PLoS One. 2016 Sep 9;11(9):e0162806. doi: 10.1371/journal.pone.0162806. eCollection 2016.
PLoS One. 2016.
PMID: 27611996
Free PMC article.
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c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance.
Pyndiah S, Tanida S, Ahmed KM, Cassimere EK, Choe C, Sakamuro D.
Pyndiah S, et al. Among authors: cassimere ek.
Sci Signal. 2011 Mar 29;4(166):ra19. doi: 10.1126/scisignal.2001556.
Sci Signal. 2011.
PMID: 21447800
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