Dereplication and chemotaxonomical studies of marine algae of the Ochrophyta and Rhodophyta phyla

Robert Brkljača; Emrehan Semih Gӧker; Sylvia Urban

doi:10.3390/md13052714

Dereplication and chemotaxonomical studies of marine algae of the Ochrophyta and Rhodophyta phyla

Mar Drugs. 2015 Apr 30;13(5):2714-31. doi: 10.3390/md13052714.

Authors

Robert Brkljača¹, Emrehan Semih Gӧker², Sylvia Urban³

Affiliations

¹ School of Applied Sciences (Discipline of Chemistry), Health Innovations Research Institute (HIRi), RMIT University, GPO Box 2476V Melbourne, Victoria 3001, Australia. robert.brkljaca@rmit.edu.au.
² School of Applied Sciences (Discipline of Chemistry), Health Innovations Research Institute (HIRi), RMIT University, GPO Box 2476V Melbourne, Victoria 3001, Australia. emrehan_goker@hotmail.com.
³ School of Applied Sciences (Discipline of Chemistry), Health Innovations Research Institute (HIRi), RMIT University, GPO Box 2476V Melbourne, Victoria 3001, Australia. sylvia.urban@rmit.edu.au.

Abstract

Dereplication and chemotaxonomic studies of six marine algae of the Ochrophyta and one of the Rhodophyta phyla resulted in the detection of 22 separate compounds. All 16 secondary metabolites, including four new compounds (16-19), could be rapidly dereplicated using HPLC-NMR and HPLC-MS methodologies in conjunction with the MarinLit database. This study highlights the advantages of using NMR data (acquired via HPLC-NMR) for database searching and for the overall dereplication of natural products.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biological Products / chemistry*
Chromatography, High Pressure Liquid / methods
Databases, Factual
Magnetic Resonance Spectroscopy / methods
Rhodophyta / chemistry*

Substances

Biological Products