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Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.
Loaëc N, Attanasio E, Villiers B, Durieu E, Tahtouh T, Cam M, Davis RA, Alencar A, Roué M, Bourguet-Kondracki ML, Proksch P, Limanton E, Guiheneuf S, Carreaux F, Bazureau JP, Klautau M, Meijer L. Loaëc N, et al. Among authors: limanton e. Mar Drugs. 2017 Oct 17;15(10):316. doi: 10.3390/md15100316. Mar Drugs. 2017. PMID: 29039762 Free PMC article. Review.
Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors.
Tahtouh T, Durieu E, Villiers B, Bruyère C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, Sévère E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, Burgy G, Guiheneuf S, Herault Y, Kendall DA, Carreaux F, Bazureau JP, Meijer L. Tahtouh T, et al. Among authors: limanton e. J Med Chem. 2022 Jan 27;65(2):1396-1417. doi: 10.1021/acs.jmedchem.1c01141. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928152
From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines.
Lassagne F, Langlais T, Caytan E, Limanton E, Paquin L, Boullard M, Courtel C, Curbet I, Gédéon C, Lebreton J, Picot L, Thiéry V, Souab M, Baratte B, Ruchaud S, Bach S, Roisnel T, Mongin F. Lassagne F, et al. Among authors: limanton e. Molecules. 2018 Nov 13;23(11):2961. doi: 10.3390/molecules23112961. Molecules. 2018. PMID: 30428591 Free PMC article.
Electron Transfer Kinetics in a Deep Eutectic Solvent.
Zhen F, Percevault L, Paquin L, Limanton E, Lagrost C, Hapiot P. Zhen F, et al. Among authors: limanton e. J Phys Chem B. 2020 Feb 13;124(6):1025-1032. doi: 10.1021/acs.jpcb.9b09022. Epub 2020 Feb 4. J Phys Chem B. 2020. PMID: 31972091 Free article.
Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A.
Bourahla K, Guihéneuf S, Limanton E, Paquin L, Le Guével R, Charlier T, Rahmouni M, Durieu E, Lozach O, Carreaux F, Meijer L, Bazureau JP. Bourahla K, et al. Among authors: limanton e. Pharmaceuticals (Basel). 2021 Oct 27;14(11):1086. doi: 10.3390/ph14111086. Pharmaceuticals (Basel). 2021. PMID: 34832868 Free PMC article.
Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice.
Souchet B, Audrain M, Billard JM, Dairou J, Fol R, Orefice NS, Tada S, Gu Y, Dufayet-Chaffaud G, Limanton E, Carreaux F, Bazureau JP, Alves S, Meijer L, Janel N, Braudeau J, Cartier N. Souchet B, et al. Among authors: limanton e. Acta Neuropathol Commun. 2019 Mar 18;7(1):46. doi: 10.1186/s40478-019-0678-6. Acta Neuropathol Commun. 2019. PMID: 30885273 Free PMC article.
cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.
Fant X, Durieu E, Chicanne G, Payrastre B, Sbrissa D, Shisheva A, Limanton E, Carreaux F, Bazureau JP, Meijer L. Fant X, et al. Among authors: limanton e. Mol Pharmacol. 2014 Mar;85(3):441-50. doi: 10.1124/mol.113.090837. Epub 2013 Dec 23. Mol Pharmacol. 2014. PMID: 24366666 Free PMC article.