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Children with Early-Onset Psychosis Have Increased Burden of Rare GRIN2A Variants.
Hojlo MA, Ghebrelul M, Genetti CA, Smith R, Rockowitz S, Deaso E, Beggs AH, Agrawal PB, Glahn DC, Gonzalez-Heydrich J, Brownstein CA. Hojlo MA, et al. Among authors: deaso e. Genes (Basel). 2023 Mar 23;14(4):779. doi: 10.3390/genes14040779. Genes (Basel). 2023. PMID: 37107537 Free PMC article.
Similar Rates of Deleterious Copy Number Variants in Early-Onset Psychosis and Autism Spectrum Disorder.
Brownstein CA, Douard E, Mollon J, Smith R, Hojlo MA, Das A, Goldman M, Garvey E, Cabral K, Li J, Bowen J, Rao AS, Genetti C, Carroll D, Knowles EEM, Deaso E, Agrawal PB, Beggs AH, D'Angelo E, Almasy L, Alexander-Bloch A, Saci Z, Moreau CA, Huguet G, Deo AJ, Jacquemont S, Glahn DC, Gonzalez-Heydrich J. Brownstein CA, et al. Among authors: deaso e. Am J Psychiatry. 2022 Nov 1;179(11):853-861. doi: 10.1176/appi.ajp.21111175. Epub 2022 Aug 24. Am J Psychiatry. 2022. PMID: 36000218 Free PMC article.
RCL1 copy number variants are associated with a range of neuropsychiatric phenotypes.
Brownstein CA, Smith RS, Rodan LH, Gorman MP, Hojlo MA, Garvey EA, Li J, Cabral K, Bowen JJ, Rao AS, Genetti CA, Carroll D, Deaso EA, Agrawal PB, Rosenfeld JA, Bi W, Howe J, Stavropoulos DJ, Hansen AW, Hamoda HM, Pinard F, Caracansi A, Walsh CA, D'Angelo EJ, Beggs AH, Zarrei M, Gibbs RA, Scherer SW, Glahn DC, Gonzalez-Heydrich J. Brownstein CA, et al. Among authors: deaso ea. Mol Psychiatry. 2021 May;26(5):1706-1718. doi: 10.1038/s41380-021-01035-y. Epub 2021 Feb 17. Mol Psychiatry. 2021. PMID: 33597717 Free PMC article.
Dose-Related Target Occupancy and Effects on Circuitry, Behavior, and Neuroplasticity of the Glycine Transporter-1 Inhibitor PF-03463275 in Healthy and Schizophrenia Subjects.
D'Souza DC, Carson RE, Driesen N, Johannesen J, Ranganathan M, Krystal JH; Yale GlyT1 Study Group. D'Souza DC, et al. Biol Psychiatry. 2018 Sep 15;84(6):413-421. doi: 10.1016/j.biopsych.2017.12.019. Epub 2018 Jan 31. Biol Psychiatry. 2018. PMID: 29499855 Free PMC article. Clinical Trial.
Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: a double-blind, placebo-controlled, parallel group, phase 2a single-site randomised controlled trial.
D'Souza DC, Cortes-Briones J, Creatura G, Bluez G, Thurnauer H, Deaso E, Bielen K, Surti T, Radhakrishnan R, Gupta A, Gupta S, Cahill J, Sherif MA, Makriyannis A, Morgan PT, Ranganathan M, Skosnik PD. D'Souza DC, et al. Among authors: deaso e. Lancet Psychiatry. 2019 Jan;6(1):35-45. doi: 10.1016/S2215-0366(18)30427-9. Epub 2018 Dec 6. Lancet Psychiatry. 2019. PMID: 30528676 Clinical Trial.