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Page 1
Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.
Silva-Cayetano A, Fra-Bido S, Robert PA, Innocentin S, Burton AR, Watson EM, Lee JL, Webb LMC, Foster WS, McKenzie RCJ, Bignon A, Vanderleyden I, Alterauge D, Lemos JP, Carr EJ, Hill DL, Cinti I, Balabanian K, Baumjohann D, Espeli M, Meyer-Hermann M, Denton AE, Linterman MA. Silva-Cayetano A, et al. Nat Immunol. 2023 Jul;24(7):1124-1137. doi: 10.1038/s41590-023-01519-9. Epub 2023 May 22. Nat Immunol. 2023. PMID: 37217705 Free PMC article.
A functional GC requires the co-ordination of multiple cell types across time and space, in particular across its two functionally distinct compartments: the light and dark zones. In aged mice, there is CXCR4-mediated mislocalization of T follicular helper (T(FH)) cells to …
A functional GC requires the co-ordination of multiple cell types across time and space, in particular across its two functionally distinct …
Haematopoiesis, or Blood Poetry.
Lake J. Lake J. Perspect Biol Med. 2020;63(4):683-694. doi: 10.1353/pbm.2020.0055. Perspect Biol Med. 2020. PMID: 33416805
In a small impersonal room opposite a stranger while I sip a glass of water? In a series of dark jokes with my husband in the kitchen late at night? In snatches of awkward conversation with friends? ...From the discoveries of Paul Ehrlich to the scattered words of Emily …
In a small impersonal room opposite a stranger while I sip a glass of water? In a series of dark jokes with my husband in the kitchen …
Interaction of memory systems is controlled by context in both food-storing and non-storing birds.
Brown EK, Strang CG, Sherry DF, Hampton RR. Brown EK, et al. Learn Behav. 2022 Mar;50(1):140-152. doi: 10.3758/s13420-021-00496-z. Epub 2021 Dec 16. Learn Behav. 2022. PMID: 34918201 Free PMC article.
While both black-capped chickadees (Poecile atricapillus) and dark-eyed juncos (Junco hyemalis) are under selective pressure to remember reliable long-term spatial locations (habit memory), chickadees must additionally quickly form and rapidly update spatial memory for uni …
While both black-capped chickadees (Poecile atricapillus) and dark-eyed juncos (Junco hyemalis) are under selective pressure to remem …
Novel perfluoroalkyl substances (PFAS) discovered in whole blood using automated non-targeted analysis of dried blood spots.
Koelmel JP, Lin EZ, Parry E, Stelben P, Rennie EE, Godri Pollitt KJ. Koelmel JP, et al. Sci Total Environ. 2023 Jul 20;883:163579. doi: 10.1016/j.scitotenv.2023.163579. Epub 2023 Apr 24. Sci Total Environ. 2023. PMID: 37100129
Most of these novel PFAS have not been previously identified. Non-targeted methods are required to characterize this "dark matter" PFAS. Our objective was to apply non-targeted PFAS analysis to human blood to gain an understanding about the sources, concentrations, and tox …
Most of these novel PFAS have not been previously identified. Non-targeted methods are required to characterize this "dark matter" PF …
Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency.
Longo KA, Berryman DE, Kelder B, Charoenthongtrakul S, Distefano PS, Geddes BJ, Kopchick JJ. Longo KA, et al. Growth Horm IGF Res. 2010 Feb;20(1):73-9. doi: 10.1016/j.ghir.2009.08.002. Epub 2009 Sep 10. Growth Horm IGF Res. 2010. PMID: 19747867 Free PMC article.
Additionally, GHR -/- mice had higher ratios of caloric intake to EE at several intervals during the dark phase, and this effect was greater and more sustained in the final 3h of the dark phase. ...While GHR -/- mice oxidized a greater proportion of lipid during the …
Additionally, GHR -/- mice had higher ratios of caloric intake to EE at several intervals during the dark phase, and this effect was …
Circadian time-place (or time-route) learning in rats with hippocampal lesions.
Cole E, Mistlberger RE, Merza D, Trigiani LJ, Madularu D, Simundic A, Mumby DG. Cole E, et al. Neurobiol Learn Mem. 2016 Dec;136:236-243. doi: 10.1016/j.nlm.2016.09.004. Epub 2016 Sep 10. Neurobiol Learn Mem. 2016. PMID: 27622983
Probe tests revealed that the rats were not using an alternation strategy or relying on light-dark transitions to locate the food reward. We hypothesize that transient disruption and recovery reflect a switch from HPC-dependent allocentric navigation (learning places) to d …
Probe tests revealed that the rats were not using an alternation strategy or relying on light-dark transitions to locate the food rew …
Physicians' Human Papillomavirus Vaccine Communication With Parents of Different Skin Color: Feasibility of Measuring Indicators of Implicit Bias With Virtual Reality.
Popler E, Rosen BL, Meisman AR, Lee MR, Kahn JA, Chandler EL, Klein MD, Real FJ. Popler E, et al. J Adolesc Health. 2024 Mar 15:S1054-139X(24)00107-1. doi: 10.1016/j.jadohealth.2024.02.017. Online ahead of print. J Adolesc Health. 2024. PMID: 38493391
METHODS: Physicians (N = 90) at an academic primary care center were recruited for a VR study in which they counseled dark or light-skinned parent avatars who expressed hesitation about human papillomavirus vaccination for their adolescent child. ...RESULTS: Both direct (e …
METHODS: Physicians (N = 90) at an academic primary care center were recruited for a VR study in which they counseled dark or light-s …
"It's not just the medical aspects that are important": A qualitative exploration of first-time parents' experiences of antenatal imaging and their influence on parent-fetal bonding.
Skelton E, Cromb D, Smith A, van Poppel MPM, Morland C, Harrison G, Rutherford M, Malamateniou C, Ayers S. Skelton E, et al. Radiography (Lond). 2024 Jan;30(1):288-295. doi: 10.1016/j.radi.2023.11.019. Epub 2023 Dec 7. Radiography (Lond). 2024. PMID: 38064765 Free article.
RESULTS: The analysis generated three themes: 1) Our baby, our scan too; 2) Destination parenthood; and 3) Being in the dark, then finding the light. These themes highlight the important, but transient role of antenatal imaging in enhancing parent-fetal bonding, as well as …
RESULTS: The analysis generated three themes: 1) Our baby, our scan too; 2) Destination parenthood; and 3) Being in the dark, then fi …
17 results