Angiogenesis model with Erlang distributed delays

Math Biosci Eng. 2017 Feb 1;14(1):1-15. doi: 10.3934/mbe.2017001.

Abstract

We consider the model of angiogenesis process proposed by Bodnar and Foryś (2009) with time delays included into the vessels formation and tumour growth processes. Originally, discrete delays were considered, while in the present paper we focus on distributed delays and discuss specific results for the Erlang distributions. Analytical results concerning stability of positive steady states are illustrated by numerical results in which we also compare these results with those for discrete delays.

MeSH terms

  • Humans
  • Models, Biological*
  • Neoplasms / blood supply*
  • Neovascularization, Pathologic*