Pharmacologic Application Potentials of Sulfated Polysaccharide from Marine Algae

Polymers (Basel). 2019 Jul 8;11(7):1163. doi: 10.3390/polym11071163.

Abstract

With the advent of exploration in finding new sources for treating different diseases, one possible natural source is from marine algae. Having an array of potential benefits, researchers are interested in the components which comprise one of these activities. This can lead to the isolation of active compounds with biological activities, such as antioxidation of free radicals, anti-inflammation, antiproliferation of cancer cells, and anticoagulant to name a few. One of the compounds that are isolated from marine algae are sulfated polysaccharides (SPs). SPs are complex heterogenous natural polymers with an abundance found in different species of marine algae. Marine algae are known to be one of the most important sources of SPs, and depending on the species, its chemical structure varies. This variety has important physical and chemical components and functions which has gained the attention of researchers as this contributes to the many facets of its pharmacologic activity. In this review, recent pharmacologic application potentials and updates on the use of SPs from marine algae are discussed.

Keywords: bioactivity; marine algae; natural polymers; pharmacologic activity; seaweeds; sulfated polysaccharides; therapeutics.

Publication types

  • Review