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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1992 1
2001 1
2002 1
2003 2
2007 1
2008 1
2009 2
2010 2
2011 1
2012 2
2014 3
2015 3
2016 4
2017 2
2018 4
2019 3
2020 3
2021 3
2022 3
2023 2
2024 0

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39 results

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Page 1
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Zatreanu D, Robinson HMR, Alkhatib O, Boursier M, Finch H, Geo L, Grande D, Grinkevich V, Heald RA, Langdon S, Majithiya J, McWhirter C, Martin NMB, Moore S, Neves J, Rajendra E, Ranzani M, Schaedler T, Stockley M, Wiggins K, Brough R, Sridhar S, Gulati A, Shao N, Badder LM, Novo D, Knight EG, Marlow R, Haider S, Callen E, Hewitt G, Schimmel J, Prevo R, Alli C, Ferdinand A, Bell C, Blencowe P, Bot C, Calder M, Charles M, Curry J, Ekwuru T, Ewings K, Krajewski W, MacDonald E, McCarron H, Pang L, Pedder C, Rigoreau L, Swarbrick M, Wheatley E, Willis S, Wong AC, Nussenzweig A, Tijsterman M, Tutt A, Boulton SJ, Higgins GS, Pettitt SJ, Smith GCM, Lord CJ. Zatreanu D, et al. Among authors: macdonald e. Nat Commun. 2021 Jun 17;12(1):3636. doi: 10.1038/s41467-021-23463-8. Nat Commun. 2021. PMID: 34140467 Free PMC article.
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
Stockley ML, Ferdinand A, Benedetti G, Blencowe P, Boyd SM, Calder M, Charles MD, Edwardes LV, Ekwuru T, Finch H, Galbiati A, Geo L, Grande D, Grinkevich V, Holliday ND, Krajewski WW, MacDonald E, Majithiya JB, McCarron H, McWhirter CL, Patel V, Pedder C, Rajendra E, Ranzani M, Rigoreau LJM, Robinson HMR, Schaedler T, Sirina J, Smith GCM, Swarbrick ME, Turnbull AP, Willis S, Heald RA. Stockley ML, et al. Among authors: macdonald e. J Med Chem. 2022 Oct 27;65(20):13879-13891. doi: 10.1021/acs.jmedchem.2c01142. Epub 2022 Oct 6. J Med Chem. 2022. PMID: 36200480
Identification and optimization of a novel series of selective PIP5K inhibitors.
Andrews DM, Cartic S, Cosulich S, Divecha N, Faulder P, Flemington V, Kern O, Kettle JG, MacDonald E, McKelvie J, Pike KG, Roberts B, Rowlinson R, Smith JM, Stockley M, Swarbrick ME, Treinies I, Waring MJ. Andrews DM, et al. Among authors: macdonald e. Bioorg Med Chem. 2022 Jan 15;54:116557. doi: 10.1016/j.bmc.2021.116557. Epub 2021 Dec 12. Bioorg Med Chem. 2022. PMID: 34922306
Estimating retention benchmarks for salvage logging to protect biodiversity.
Thorn S, Chao A, Georgiev KB, Müller J, Bässler C, Campbell JL, Castro J, Chen YH, Choi CY, Cobb TP, Donato DC, Durska E, Macdonald E, Feldhaar H, Fontaine JB, Fornwalt PJ, Hernández RMH, Hutto RL, Koivula M, Lee EJ, Lindenmayer D, Mikusiński G, Obrist MK, Perlík M, Rost J, Waldron K, Wermelinger B, Weiß I, Żmihorski M, Leverkus AB. Thorn S, et al. Among authors: macdonald e. Nat Commun. 2020 Sep 21;11(1):4762. doi: 10.1038/s41467-020-18612-4. Nat Commun. 2020. PMID: 32958767 Free PMC article.
Data on vegetation across forest edges from the FERN (Forest Edge Research Network).
Harper KA, Gray L, Macdonald SE, Lesieur D, DeFields D, Dodonov P, Franklin CMA, Haughian SR, Mascarúa López L, Heathcote A, Jager K, Yang R, Angelidis C, Braga AL, Butler W, Coley S, Kornelsen JME, Murphy L, Pelton J, Recco EV, de Oliveira Xavier R, Wilson I, Ribeiro MC, da Silva Matos DM, Bergeron Y. Harper KA, et al. Among authors: macdonald se. Ecology. 2023 Jul;104(7):e4098. doi: 10.1002/ecy.4098. Epub 2023 May 31. Ecology. 2023. PMID: 37258300
Discovery of potent inhibitors of the lysophospholipase autotaxin.
Shah P, Cheasty A, Foxton C, Raynham T, Farooq M, Gutierrez IF, Lejeune A, Pritchard M, Turnbull A, Pang L, Owen P, Boyd S, Stowell A, Jordan A, Hamilton NM, Hitchin JR, Stockley M, MacDonald E, Quesada MJ, Trivier E, Skeete J, Ovaa H, Moolenaar WH, Ryder H. Shah P, et al. Among authors: macdonald e. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5403-5410. doi: 10.1016/j.bmcl.2016.10.036. Epub 2016 Oct 14. Bioorg Med Chem Lett. 2016. PMID: 27780639
Correction to "Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta".
Stockley ML, Benedetti G, Blencowe P, Boulton SJ, Boyd SM, Calder M, Charles MD, Edwardes LV, Ekwuru T, Ferdinand A, Finch H, Galbiati A, Geo L, Grande D, Grinkevich V, Higgins GS, Holliday ND, Krajewski WW, MacDonald E, Majithiya JB, McCarron H, McWhirter CL, Patel V, Pedder C, Rajendra E, Ranzani M, Rigoreau LJM, Robinson HMR, Schaedler T, Sirina J, Smith GCM, Swarbrick ME, Turnbull AP, Willis S, Zemla A, Heald RA. Stockley ML, et al. Among authors: macdonald e. J Med Chem. 2023 Feb 23. doi: 10.1021/acs.jmedchem.3c00204. Online ahead of print. J Med Chem. 2023. PMID: 36815444 No abstract available.
Frailty index to measure health status in people with systemic sclerosis.
Rockwood MR, MacDonald E, Sutton E, Rockwood K, Baron M; Canadian Scleroderma Research Group. Rockwood MR, et al. Among authors: macdonald e. J Rheumatol. 2014 Apr;41(4):698-705. doi: 10.3899/jrheum.130182. Epub 2014 Mar 1. J Rheumatol. 2014. PMID: 24584923
39 results