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Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy.
Garai S, Leo LM, Szczesniak AM, Hurst DP, Schaffer PC, Zagzoog A, Black T, Deschamps JR, Miess E, Schulz S, Janero DR, Straiker A, Pertwee RG, Abood ME, Kelly MEM, Reggio PH, Laprairie RB, Thakur GA. Garai S, et al. Among authors: miess e. J Med Chem. 2021 Jun 24;64(12):8104-8126. doi: 10.1021/acs.jmedchem.1c00040. Epub 2021 Apr 7. J Med Chem. 2021. PMID: 33826336
Differentiation of opioid drug effects by hierarchical multi-site phosphorylation.
Just S, Illing S, Trester-Zedlitz M, Lau EK, Kotowski SJ, Miess E, Mann A, Doll C, Trinidad JC, Burlingame AL, von Zastrow M, Schulz S. Just S, et al. Among authors: miess e. Mol Pharmacol. 2013 Mar;83(3):633-9. doi: 10.1124/mol.112.082875. Epub 2012 Dec 13. Mol Pharmacol. 2013. PMID: 23239825 Free PMC article.
The CENP-T C-terminus is exclusively proximal to H3.1 and not to H3.2 or H3.3.
Abendroth C, Hofmeister A, Hake SB, Kamweru PK, Miess E, Dornblut C, Küffner I, Deng W, Leonhardt H, Orthaus S, Hoischen C, Diekmann S. Abendroth C, et al. Among authors: miess e. Int J Mol Sci. 2015 Mar 12;16(3):5839-63. doi: 10.3390/ijms16035839. Int J Mol Sci. 2015. PMID: 25775162 Free PMC article.