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Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma.
Cerqua I, Granato E, Corvino A, Severino B, D'Avino D, Simonelli M, Perissutti E, Scognamiglio A, Mirra D, D'Agostino B, Caliendo G, Rossi A, Cirino G, Motta CM, Roviezzo F. Cerqua I, et al. Among authors: granato e. Front Pharmacol. 2023 Oct 12;14:1266934. doi: 10.3389/fphar.2023.1266934. eCollection 2023. Front Pharmacol. 2023. PMID: 37900172 Free PMC article.
Antagonizing S1P3 Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis.
Corvino A, Cerqua I, Lo Bianco A, Caliendo G, Fiorino F, Frecentese F, Magli E, Morelli E, Perissutti E, Santagada V, Cirino G, Granato E, Roviezzo F, Puliti E, Bernacchioni C, Lavecchia A, Donati C, Severino B. Corvino A, et al. Among authors: granato e. Int J Mol Sci. 2021 Aug 17;22(16):8861. doi: 10.3390/ijms22168861. Int J Mol Sci. 2021. PMID: 34445567 Free PMC article.
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy.
Cerqua I, Granato E, Petti A, Pavese R, Costa SKP, Feitosa KB, Soares AG, Muscara M, Camerlingo R, Rea G, Fiorino F, Santagada V, Frecentese F, Cirino G, Caliendo G, Severino B, Roviezzo F. Cerqua I, et al. Among authors: granato e. Pharmacol Res. 2022 Dec;186:106536. doi: 10.1016/j.phrs.2022.106536. Epub 2022 Nov 1. Pharmacol Res. 2022. PMID: 36332810
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization.
Cerqua I, Musella S, Peltner LK, D'Avino D, Di Sarno V, Granato E, Vestuto V, Di Matteo R, Pace S, Ciaglia T, Bilancia R, Smaldone G, Di Matteo F, Di Micco S, Bifulco G, Pepe G, Basilicata MG, Rodriquez M, Gomez-Monterrey IM, Campiglia P, Ostacolo C, Roviezzo F, Werz O, Rossi A, Bertamino A. Cerqua I, et al. Among authors: granato e. J Med Chem. 2022 Nov 10;65(21):14456-14480. doi: 10.1021/acs.jmedchem.2c00817. Epub 2022 Nov 1. J Med Chem. 2022. PMID: 36318728 Free PMC article.
A vitamin E long-chain metabolite and the inspired drug candidate α-amplexichromanol relieve asthma features in an experimental model of allergen sensitization.
Cerqua I, Neukirch K, Terlizzi M, Granato E, Caiazzo E, Cicala C, Ialenti A, Capasso R, Werz O, Sorrentino R, Seraphin D, Helesbeux JJ, Cirino G, Koeberle A, Roviezzo F, Rossi A. Cerqua I, et al. Among authors: granato e. Pharmacol Res. 2022 Jul;181:106250. doi: 10.1016/j.phrs.2022.106250. Epub 2022 May 10. Pharmacol Res. 2022. PMID: 35562015