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Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes.
Benzoni P, Campostrini G, Landi S, Bertini V, Marchina E, Iascone M, Ahlberg G, Olesen MS, Crescini E, Mora C, Bisleri G, Muneretto C, Ronca R, Presta M, Poliani PL, Piovani G, Verardi R, Di Pasquale E, Consiglio A, Raya A, Torre E, Lodrini AM, Milanesi R, Rocchetti M, Baruscotti M, DiFrancesco D, Memo M, Barbuti A, Dell'Era P. Benzoni P, et al. Among authors: crescini e. Cardiovasc Res. 2020 May 1;116(6):1147-1160. doi: 10.1093/cvr/cvz217. Cardiovasc Res. 2020. PMID: 31504264 Free PMC article.
The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization.
Ruzzenenti P, Asperti M, Mitola S, Crescini E, Maccarinelli F, Gryzik M, Regoni M, Finazzi D, Arosio P, Poli M. Ruzzenenti P, et al. Among authors: crescini e. Biochim Biophys Acta. 2015 Jun;1850(6):1267-73. doi: 10.1016/j.bbagen.2015.02.016. Epub 2015 Mar 5. Biochim Biophys Acta. 2015. PMID: 25749565