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PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
Raab M, Sanhaji M, Matthess Y, Hörlin A, Lorenz I, Dötsch C, Habbe N, Waidmann O, Kurunci-Csacsko E, Firestein R, Becker S, Strebhardt K. Raab M, et al. Among authors: kurunci csacsko e. Nat Commun. 2018 Mar 16;9(1):1106. doi: 10.1038/s41467-018-03494-4. Nat Commun. 2018. PMID: 29549256 Free PMC article.
Sequential Targeting of PLK1 and PARP1 Reverses the Resistance to PARP Inhibitors and Enhances Platin-Based Chemotherapy in BRCA-Deficient High-Grade Serous Ovarian Cancer with KRAS Amplification.
Gasimli K, Raab M, Tahmasbi Rad M, Kurunci-Csacsko E, Becker S, Strebhardt K, Sanhaji M. Gasimli K, et al. Among authors: kurunci csacsko e. Int J Mol Sci. 2022 Sep 17;23(18):10892. doi: 10.3390/ijms231810892. Int J Mol Sci. 2022. PMID: 36142803 Free PMC article.
Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1.
Raab M, Krämer A, Hehlgans S, Sanhaji M, Kurunci-Csacsko E, Dötsch C, Bug G, Ottmann O, Becker S, Pachl F, Kuster B, Strebhardt K. Raab M, et al. Among authors: kurunci csacsko e. Mol Oncol. 2015 Jan;9(1):140-54. doi: 10.1016/j.molonc.2014.07.020. Epub 2014 Aug 11. Mol Oncol. 2015. PMID: 25169932 Free PMC article.
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.
Raab M, Kappel S, Krämer A, Sanhaji M, Matthess Y, Kurunci-Csacsko E, Calzada-Wack J, Rathkolb B, Rozman J, Adler T, Busch DH, Esposito I, Fuchs H, Gailus-Durner V, Klingenspor M, Wolf E, Sänger N, Prinz F, Angelis MH, Seibler J, Yuan J, Bergmann M, Knecht R, Kreft B, Strebhardt K. Raab M, et al. Among authors: kurunci csacsko e. Nat Commun. 2011 Jul 19;2:395. doi: 10.1038/ncomms1395. Nat Commun. 2011. PMID: 21772266 Free PMC article.