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Melatonin decreases IRF-3 protein expression in the gastrocnemius muscle, reduces IL-1β and LPS plasma concentrations, and improves the lipid profile in rats with apical periodontitis fed on a high-fat diet.
Dos Santos RM, Belardi BE, Tsosura TVS, Chiba FY, Mattera MSLC, Machado NES, Cantiga-Silva C, Carvalho NR, Bravo LT, Nobumoto ACTY, Oliveira SHP, Cintra LTA, Matsushita DH. Dos Santos RM, et al. Odontology. 2023 Jul;111(3):687-696. doi: 10.1007/s10266-022-00782-w. Epub 2022 Dec 25. Odontology. 2023. PMID: 36567367
Plasma concentrations of LPS and IL-1beta were analyzed using enzyme-linked immunosorbent assay, and the lipid profile was analyzed using biochemical tests. ...
Plasma concentrations of LPS and IL-1beta were analyzed using enzyme-linked immunosorbent assay, and the lipid p …
Melatonin decreases plasma TNF-α and improves nonenzymatic antioxidant defence and insulin sensitivity in rats with apical periodontitis fed a high-fat diet.
Dos Santos RM, Tsosura TVS, Belardi BE, Chaves-Neto AH, Chiba FY, Mattera MSLC, Tessarin GWL, Bravo LT, Cintra LTA, Matsushita DH. Dos Santos RM, et al. Int Endod J. 2023 Feb;56(2):164-178. doi: 10.1111/iej.13852. Epub 2022 Oct 29. Int Endod J. 2023. PMID: 36261317
Glycaemia, insulinaemia, homeostatic model assessment for IR index, tumour necrosis factor-alpha (TNF-alpha), and interleukin-6 were analysed in plasma using biochemical tests and enzyme-linked immunosorbent assay. Thiobarbituric acid-reactive substanc …
Glycaemia, insulinaemia, homeostatic model assessment for IR index, tumour necrosis factor-alpha (TNF-alpha), and interleukin-6 were analyse …
Effects of melatonin on insulin signaling and inflammatory pathways of rats with apical periodontitis.
Tavares BS, Tsosura TVS, Mattera MSLC, Santelli JO, Belardi BE, Chiba FY, Cintra LTA, Silva CC, Matsushita DH. Tavares BS, et al. Int Endod J. 2021 Jun;54(6):926-940. doi: 10.1111/iej.13474. Epub 2021 Jan 27. Int Endod J. 2021. PMID: 33411973
At the end of the treatment, the following were analysed: (1) plasma concentrations of insulin and inflammatory cytokines (TNF-alpha, IL-6, IL-1beta and IL-10) using ELISA kits; (2) glycaemia using enzymatic assay; (3) insulin resistance using homoeostasis model ass …
At the end of the treatment, the following were analysed: (1) plasma concentrations of insulin and inflammatory cytokines (TNF-alpha, IL-6, …
Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
Takimoto E, Belardi D, Tocchetti CG, Vahebi S, Cormaci G, Ketner EA, Moens AL, Champion HC, Kass DA. Takimoto E, et al. Circulation. 2007 Apr 24;115(16):2159-67. doi: 10.1161/CIRCULATIONAHA.106.643536. Epub 2007 Apr 9. Circulation. 2007. PMID: 17420342
Surprisingly, myocardial cGMP changed little with SIL+ISO yet rose nearly 5-fold with ANP, whereas protein kinase G activation (vasodilator-stimulated protein phosphorylation; ELISA assay) displayed the opposite: increased with SIL+ISO but unaltered by ANP+ISO. ...
Surprisingly, myocardial cGMP changed little with SIL+ISO yet rose nearly 5-fold with ANP, whereas protein kinase G activation (vasodilator- …