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Page 1
Showing results for elena noting
Search for Elena Notina instead (3 results)
Pharmacokinetics and Exposure-Response of Vosoritide in Children with Achondroplasia.
Chan ML, Qi Y, Larimore K, Cherukuri A, Seid L, Jayaram K, Jeha G, Fisheleva E, Day J, Huntsman-Labed A, Savarirayan R, Irving M, Bacino CA, Hoover-Fong J, Ozono K, Mohnike K, Wilcox WR, Horton WA, Henshaw J. Chan ML, et al. Clin Pharmacokinet. 2022 Feb;61(2):263-280. doi: 10.1007/s40262-021-01059-1. Epub 2021 Aug 25. Clin Pharmacokinet. 2022. PMID: 34431071 Free PMC article. Clinical Trial.
Total anti-vosoritide antibody (TAb) responses were detected in the serum of 25 of 60 (42%) treated patients in the phase III study, with no apparent impact of TAb development noted on annualized growth velocity or vosoritide exposure. Across the exposure range obtained wi …
Total anti-vosoritide antibody (TAb) responses were detected in the serum of 25 of 60 (42%) treated patients in the phase III study, with no …
The Role of Gender Pharmacogenetics in the Personalization of Drug Treatment.
Cecchin E, Posocco B, Mezzalira S, Appetecchia M, Toffoli G. Cecchin E, et al. J Pharmacol Exp Ther. 2023 Aug;386(2):190-197. doi: 10.1124/jpet.122.001416. Epub 2023 Mar 31. J Pharmacol Exp Ther. 2023. PMID: 37001987 Review.
A significant increase in toxicity has been described in female patients, with a more pronounced effect of specific DPYD and TYMS polymorphisms also noted. This manuscript reviews the major findings in the field of sex-specific pharmacogenomics. ...
A significant increase in toxicity has been described in female patients, with a more pronounced effect of specific DPYD and TYMS polymorphi …
Addressing delays in the diagnosis of pheochromocytoma/paraganglioma.
Ilias I, Thomopoulos C. Ilias I, et al. Expert Rev Endocrinol Metab. 2019 Sep;14(5):359-363. doi: 10.1080/17446651.2019.1657007. Epub 2019 Aug 20. Expert Rev Endocrinol Metab. 2019. PMID: 31429343 Review.
In theory the diagnosis of PPG should be straightforward. In clinical practice, however, considerable delays are noted in establishing such a diagnosis. Areas covered: We assess the characteristics of various approaches to diagnosis and localization of PPG lesions (and the …
In theory the diagnosis of PPG should be straightforward. In clinical practice, however, considerable delays are noted in establishin …
The Molecular Tumor Board of the Regina Elena National Cancer Institute: from accrual to treatment in real-world.
Giacomini P, Valenti F, Allegretti M, Pallocca M, De Nicola F, Ciuffreda L, Fanciulli M, Scalera S, Buglioni S, Melucci E, Casini B, Carosi M, Pescarmona E, Giordani E, Sperati F, Jannitti N, Betti M, Maugeri-Saccà M, Cecere FL, Villani V, Pace A, Appetecchia M, Vici P, Savarese A, Krasniqi E, Ferraresi V, Russillo M, Fabi A, Landi L, Minuti G, Cappuzzo F, Zeuli M, Ciliberto G. Giacomini P, et al. J Transl Med. 2023 Oct 16;21(1):725. doi: 10.1186/s12967-023-04595-5. J Transl Med. 2023. PMID: 37845764 Free PMC article.
Retrospectively, 8 patients receiving post-MTB treatment(s) as per physician's choice were noted to have a much longer overall survival from MTB accrual than 11 patients who had received no further treatment (35.09 vs 6.67 months, p = 0.006). ...
Retrospectively, 8 patients receiving post-MTB treatment(s) as per physician's choice were noted to have a much longer overall surviv …
Safety of extended interval dosing immune checkpoint inhibitors: a multicenter cohort study.
Cantini L, Paoloni F, Pecci F, Spagnolo F, Genova C, Tanda ET, Aerts S, Rebuzzi SE, Fornarini G, Zoratto F, Fancelli S, Lupi A, Della Corte CM, Parisi A, Bennati C, Ortega C, Atzori F, Piovano PL, Orciuolo C, De Tursi M, Ghidini M, Botticelli A, Scagnoli S, Belluomini L, Leporati R, Veccia A, Di Giacomo AM, Festino L, Cortinovis D, Acquati M, Filetti M, Giusti R, Tucci M, Sergi MC, Garutti M, Puglisi F, Manglaviti S, Citarella F, Santoni M, Rijavec E, Lo Russo G, Santini D, Addeo A, Antonuzzo L, Indini A, Rocchi MBL, Cortellini A, Grossi F, Ascierto PA, Aerts JGJV, Berardi R. Cantini L, et al. J Natl Cancer Inst. 2023 Jul 6;115(7):796-804. doi: 10.1093/jnci/djad061. J Natl Cancer Inst. 2023. PMID: 37042716 Free PMC article.
Switching to ED was associated with a lower probability of any grade irAEs (adjusted odds ratio [aOR] = 0.83, 95% confidence interval [CI] = 0.64 to 0.99; P = .047), whereas no difference for G3 or G4 events was noted (aOR = 1.55, 95% CI = 0.81 to 2.94; P = .18). Among pat …
Switching to ED was associated with a lower probability of any grade irAEs (adjusted odds ratio [aOR] = 0.83, 95% confidence interval [CI] = …
A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.
Mascarenhas J, Migliaccio AR, Kosiorek H, Bhave R, Palmer J, Kuykendall A, Mesa R, Rampal RK, Gerds AT, Yacoub A, Pettit K, Talpaz M, Komrokji R, Kremyanskaya M, Gonzalez A, Fabris F, Johnson K, Dougherty M, McGovern E, Arango Ossa J, Domenico D, Farnoud N, Weinberg RS, Kong A, Najfeld V, Vannucchi AM, Arciprete F, Zingariello M, Falchi M, Salama ME, Mead-Harvey C, Dueck A, Varricchio L, Hoffman R. Mascarenhas J, et al. Clin Cancer Res. 2023 Sep 15;29(18):3622-3632. doi: 10.1158/1078-0432.CCR-23-0276. Clin Cancer Res. 2023. PMID: 37439808 Free PMC article. Clinical Trial.
Unlike other MF-directed therapies, increases in platelet counts were noted in 81% of treated patients with three patients achieving normalization. ...
Unlike other MF-directed therapies, increases in platelet counts were noted in 81% of treated patients with three patients achieving …
Nutraceuticals and Cancer: Potential for Natural Polyphenols.
Maiuolo J, Gliozzi M, Carresi C, Musolino V, Oppedisano F, Scarano F, Nucera S, Scicchitano M, Bosco F, Macri R, Ruga S, Cardamone A, Coppoletta A, Mollace A, Cognetti F, Mollace V. Maiuolo J, et al. Nutrients. 2021 Oct 27;13(11):3834. doi: 10.3390/nu13113834. Nutrients. 2021. PMID: 34836091 Free PMC article. Review.
Thus, nutraceutical supplementation, along with current anticancer drug treatment, may be considered for better responses and compliance in patients with cancer. It should be noted, however, that when data from studies with bioactive plant preparations are discussed, it is …
Thus, nutraceutical supplementation, along with current anticancer drug treatment, may be considered for better responses and compliance in …
Microdialysis-Assessed Adipose Tissue Metabolism in Critically Ill Patients.
Ilias I, Nikitas N, Theodorakopoulou M, Dimopoulou I. Ilias I, et al. Recent Pat Endocr Metab Immune Drug Discov. 2017;11(1):32-38. doi: 10.2174/1872214811666170608114933. Recent Pat Endocr Metab Immune Drug Discov. 2017. PMID: 28595555 Review.
Specific metabolic aberrations in critically ill patients with septic shock have been noted in adipose tissue - assessed with microdialysis before becoming evident in the systemic circulation. ...
Specific metabolic aberrations in critically ill patients with septic shock have been noted in adipose tissue - assessed with microdi …
Preparations and prokinetics.
Villa F, Signorelli C, Rondonotti E, de Franchis R. Villa F, et al. Gastrointest Endosc Clin N Am. 2006 Apr;16(2):211-20. doi: 10.1016/j.giec.2006.01.020. Gastrointest Endosc Clin N Am. 2006. PMID: 16644451 Review.
It also was agreed that it is possible that preps/prokinetics improve GTT, SBTT and completeness of examination, and that keeping the patients recumbent in the right lateral position may shorten the GTT. It was noted, however, that the best type of preparation, and dose an …
It also was agreed that it is possible that preps/prokinetics improve GTT, SBTT and completeness of examination, and that keeping the patien …
Oleogels-Innovative Technological Solution for the Nutritional Improvement of Meat Products.
Perța-Crișan S, Ursachi CȘ, Chereji BD, Munteanu FD. Perța-Crișan S, et al. Foods. 2022 Dec 27;12(1):131. doi: 10.3390/foods12010131. Foods. 2022. PMID: 36613347 Free PMC article. Review.
In particular, for meat products, studies regarding successful oleogel integration in burgers, meat batters, pates, frankfurters, fermented and bologna sausages have been noted, in order to improve their nutritional profile and make them healthier by substituting for anima …
In particular, for meat products, studies regarding successful oleogel integration in burgers, meat batters, pates, frankfurters, fermented …
197 results