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2008 1
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Page 1
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis.
Abe JI, Ko KA, Kotla S, Wang Y, Paez-Mayorga J, Shin IJ, Imanishi M, Vu HT, Tao Y, Leiva-Juarez MM, Thomas TN, Medina JL, Won JH, Fujii Y, Giancursio CJ, McBeath E, Shin JH, Guzman L, Abe RJ, Taunton J, Mochizuki N, Faubion W, Cooke JP, Fujiwara K, Evans SE, Le NT. Abe JI, et al. Among authors: mcbeath e. JCI Insight. 2019 Apr 4;4(7):e125570. doi: 10.1172/jci.insight.125570. eCollection 2019 Apr 4. JCI Insight. 2019. PMID: 30944250 Free PMC article.
Endothelial activation and fibrotic changes are impeded by laminar flow-induced CHK1-SENP2 activity through mechanisms distinct from endothelial-to-mesenchymal cell transition.
Nguyen MTH, Imanishi M, Li S, Chau K, Banerjee P, Velatooru LR, Ko KA, Samanthapudi VSK, Gi YJ, Lee LL, Abe RJ, McBeath E, Deswal A, Lin SH, Palaskas NL, Dantzer R, Fujiwara K, Borchrdt MK, Turcios EB, Olmsted-Davis EA, Kotla S, Cooke JP, Wang G, Abe JI, Le NT. Nguyen MTH, et al. Among authors: mcbeath e. Front Cardiovasc Med. 2023 Aug 30;10:1187490. doi: 10.3389/fcvm.2023.1187490. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37711550 Free PMC article.
Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals.
Singh MV, Kotla S, Le NT, Ae Ko K, Heo KS, Wang Y, Fujii Y, Thi Vu H, McBeath E, Thomas TN, Jin Gi Y, Tao Y, Medina JL, Taunton J, Carson N, Dogra V, Doyley MM, Tyrell A, Lu W, Qiu X, Stirpe NE, Gates KJ, Hurley C, Fujiwara K, Maggirwar SB, Schifitto G, Abe JI. Singh MV, et al. Among authors: mcbeath e. Circulation. 2019 Feb 26;139(9):1199-1216. doi: 10.1161/CIRCULATIONAHA.118.036232. Circulation. 2019. PMID: 30586719 Free PMC article. Clinical Trial.
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation.
Kotla S, Zhang A, Imanishi M, Ko KA, Lin SH, Gi YJ, Moczygemba M, Isgandarova S, Schadler KL, Chung C, Milgrom SA, Banchs J, Yusuf SW, Amaya DN, Guo H, Thomas TN, Shen YH, Deswal A, Herrmann J, Kleinerman ES, Entman ML, Cooke JP, Schifitto G, Maggirwar SB, McBeath E, Gupte AA, Krishnan S, Patel ZS, Yoon Y, Burks JK, Fujiwara K, Brookes PS, Le NT, Hamilton DJ, Abe JI. Kotla S, et al. Among authors: mcbeath e. Redox Biol. 2021 Nov;47:102132. doi: 10.1016/j.redox.2021.102132. Epub 2021 Sep 20. Redox Biol. 2021. PMID: 34619528 Free PMC article.
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