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H3K4me3 mediates uterine leiomyoma pathogenesis via neuronal processes, synapsis components, proliferation, and Wnt/β-catenin and TGF-β pathways.
Carbajo-García MC, Juarez-Barber E, Segura-Benítez M, Faus A, Trelis A, Monleón J, Carmona-Antoñanzas G, Pellicer A, Flanagan JM, Ferrero H. Carbajo-García MC, et al. Among authors: juarez barber e. Reprod Biol Endocrinol. 2023 Jan 26;21(1):9. doi: 10.1186/s12958-023-01060-2. Reprod Biol Endocrinol. 2023. PMID: 36703136 Free PMC article. Review.
Integrative analysis of the DNA methylome and transcriptome in uterine leiomyoma shows altered regulation of genes involved in metabolism, proliferation, extracellular matrix, and vesicles.
Carbajo-García MC, Corachán A, Juárez-Barber E, Monleón J, Payá V, Trelis A, Quiñonero A, Pellicer A, Ferrero H. Carbajo-García MC, et al. Among authors: juarez barber e. J Pathol. 2022 Aug;257(5):663-673. doi: 10.1002/path.5920. Epub 2022 Jun 13. J Pathol. 2022. PMID: 35472162
Deciphering the Role of Histone Modifications in Uterine Leiomyoma: Acetylation of H3K27 Regulates the Expression of Genes Involved in Proliferation, Cell Signaling, Cell Transport, Angiogenesis and Extracellular Matrix Formation.
Carbajo-García MC, de Miguel-Gómez L, Juárez-Barber E, Trelis A, Monleón J, Pellicer A, Flanagan JM, Ferrero H. Carbajo-García MC, et al. Among authors: juarez barber e. Biomedicines. 2022 May 30;10(6):1279. doi: 10.3390/biomedicines10061279. Biomedicines. 2022. PMID: 35740301 Free PMC article.