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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 1
1953 2
1954 1
1955 1
1957 1
1963 5
1964 6
1966 1
1967 2
1969 4
1970 4
1971 3
1972 5
1974 1
1975 1
1976 4
1977 6
1978 3
1979 4
1980 2
1981 1
1982 7
1983 6
1984 11
1985 14
1986 5
1987 23
1988 23
1989 12
1990 21
1991 9
1992 31
1993 29
1994 28
1995 21
1996 26
1997 23
1998 27
1999 15
2000 24
2001 27
2002 23
2003 37
2004 33
2005 22
2006 33
2007 35
2008 46
2009 45
2010 34
2011 49
2012 49
2013 56
2014 66
2015 81
2016 103
2017 118
2018 127
2019 138
2020 179
2021 196
2022 214
2023 225
2024 98

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2,186 results

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The following term was not found in PubMed: Liberman-Pincu
Page 1
Elabela ameliorates doxorubicin-induced cardiotoxicity by promoting autophagic flux through TFEB pathway.
Chen D, Yu W, Zhong C, Hong Q, Huang G, Que D, Wang Y, Yang Y, Rui B, Zhuang Z, Liang M, Ye Z, Yan X, Lv J, Zhang R, Yan J, Yang P. Chen D, et al. Pharmacol Res. 2022 Apr;178:106186. doi: 10.1016/j.phrs.2022.106186. Epub 2022 Mar 17. Pharmacol Res. 2022. PMID: 35306141
Chloroquine, a classical autophagic flux inhibitor, blunted the improvement of ELA on cardiac dysfunction. At last, we revealed that ELA reversed DOX-induced downregulation of transcription factor EB (TFEB), and silencing TFEB by siRNA abrogated the effects of EL …
Chloroquine, a classical autophagic flux inhibitor, blunted the improvement of ELA on cardiac dysfunction. At last, we revealed that …
Early life adversity shapes neural circuit function during sensitive postnatal developmental periods.
Malave L, van Dijk MT, Anacker C. Malave L, et al. Transl Psychiatry. 2022 Aug 1;12(1):306. doi: 10.1038/s41398-022-02092-9. Transl Psychiatry. 2022. PMID: 35915071 Free PMC article. Review.
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological mechanisms by which ELA increases the risk for future psychopathology are still poorly understood. ...We also discuss how gene-by-environment (GxE) interactions can determi …
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological mechanisms by which ELA increase …
Early life adversity as a risk factor for cognitive impairment and Alzheimer's disease.
Huang Z, Jordan JD, Zhang Q. Huang Z, et al. Transl Neurodegener. 2023 May 12;12(1):25. doi: 10.1186/s40035-023-00355-z. Transl Neurodegener. 2023. PMID: 37173751 Free PMC article. Review.
In rodent models, exposure to ELA results in specific cognitive deficits and aggravated AD pathology. ...Additionally, we discuss several interventions that may alleviate adverse consequences of ELA. Further investigation into this crucial area will help improve …
In rodent models, exposure to ELA results in specific cognitive deficits and aggravated AD pathology. ...Additionally, we discuss sev …
Early life adversity across different cell- types in the brain.
Warhaftig G, Almeida D, Turecki G. Warhaftig G, et al. Neurosci Biobehav Rev. 2023 May;148:105113. doi: 10.1016/j.neubiorev.2023.105113. Epub 2023 Feb 28. Neurosci Biobehav Rev. 2023. PMID: 36863603 Review.
As ELA has a lasting impact on the brain at a developmental stage, recent findings from the field highlighted the specific contributions of different cell types to ELA and their association with long lasting consequences. ...The findings reviewed and summarized here …
As ELA has a lasting impact on the brain at a developmental stage, recent findings from the field highlighted the specific contributi …
Elabela-APJ axis mediates angiogenesis via YAP/TAZ pathway in cerebral ischemia/reperfusion injury.
Li W, Xu P, Kong L, Feng S, Shen N, Huang H, Wang W, Xu X, Wang X, Wang G, Zhang Y, Sun W, Hu W, Liu X. Li W, et al. Transl Res. 2023 Jul;257:78-92. doi: 10.1016/j.trsl.2023.02.002. Epub 2023 Feb 21. Transl Res. 2023. PMID: 36813109
We aimed to investigate the function of endothelial ELA on post-ischemic cerebral angiogenesis. Here, we demonstrated that the endothelial ELA expression was upregulated in the ischemic brain and treatment with ELA-32 mitigated brain injury and enhanced the r …
We aimed to investigate the function of endothelial ELA on post-ischemic cerebral angiogenesis. Here, we demonstrated that the endoth …
Addressing the biological embedding of early life adversities (ELA) among adults through mindfulness: Proposed mechanisms and review of converging evidence.
Sun S, Sheridan MA, Tyrka AR, Donofry SD, Erickson KI, Loucks EB. Sun S, et al. Neurosci Biobehav Rev. 2022 Mar;134:104526. doi: 10.1016/j.neubiorev.2022.104526. Epub 2022 Jan 5. Neurosci Biobehav Rev. 2022. PMID: 34998833 Free PMC article. Review.
This paper presents evidence for mindfulness training to reduce the elevated mental and physical health risks linked to ELA among adults by targeting biological mechanisms of ELA leading to these adverse health outcomes. We first provide a brief overview of ELA …
This paper presents evidence for mindfulness training to reduce the elevated mental and physical health risks linked to ELA among adu …
A promising therapeutic peptide and preventive/diagnostic biomarker for age-related diseases: The Elabela/Apela/Toddler peptide.
Monastero R, Magro D, Venezia M, Pisano C, Balistreri CR. Monastero R, et al. Ageing Res Rev. 2023 Nov;91:102076. doi: 10.1016/j.arr.2023.102076. Epub 2023 Sep 29. Ageing Res Rev. 2023. PMID: 37776977 Free article. Review.
Elabela (ELA), Apela or Toddler peptide is a hormone peptide belonging to the adipokine group and a component of apelinergic system, discovered in 2013-2014. Given its high homology with apelin, the first ligand of APJ receptor, ELA likely mediates similar effects. …
Elabela (ELA), Apela or Toddler peptide is a hormone peptide belonging to the adipokine group and a component of apelinergic system, …
Therapeutic potential of apelin and Elabela in cardiovascular disease.
Gao S, Chen H. Gao S, et al. Biomed Pharmacother. 2023 Oct;166:115268. doi: 10.1016/j.biopha.2023.115268. Epub 2023 Aug 8. Biomed Pharmacother. 2023. PMID: 37562237 Free article. Review.
Apelin and Elabela (Ela) are peptides encoded by APLN and APELA, respectively, which act on their receptor APJ and play crucial roles in the body. ...Evidences indicated that apelin and Ela play important roles in cardiovascular diseases, and there are many studies …
Apelin and Elabela (Ela) are peptides encoded by APLN and APELA, respectively, which act on their receptor APJ and play crucial roles …
Early-life adversity, epigenetics, and visceral hypersensitivity.
Liu S, Hagiwara SI, Bhargava A. Liu S, et al. Neurogastroenterol Motil. 2017 Sep;29(9):10.1111/nmo.13170. doi: 10.1111/nmo.13170. Neurogastroenterol Motil. 2017. PMID: 28782197 Free PMC article. Review.
In animal studies, visceral hypersensitivity has been linked to several early-life adverse (ELA) events. In humans, IBD, functional dyspepsia, and IBS can have adult onset, though the adverse events that lead to visceral hypersensitivity are largely uncharacterized. In thi …
In animal studies, visceral hypersensitivity has been linked to several early-life adverse (ELA) events. In humans, IBD, functional d …
The Elabela-APJ axis: a promising therapeutic target for heart failure.
Ma Z, Song JJ, Martin S, Yang XC, Zhong JC. Ma Z, et al. Heart Fail Rev. 2021 Sep;26(5):1249-1258. doi: 10.1007/s10741-020-09957-5. Heart Fail Rev. 2021. PMID: 32314083 Free PMC article. Review.
The beneficial effects of the ELA-APJ receptor system are well-established by treating hypertension, myocardial infarction, and HF. ...Thus, targeting the ELA-APJ axis has emerged as a pre-warning biomarker and a novel therapeutic approach against progression of HF. …
The beneficial effects of the ELA-APJ receptor system are well-established by treating hypertension, myocardial infarction, and HF. . …
2,186 results