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Page 1
Pioglitazone as an adjuvant of amphotericin B for the treatment of cryptococcosis.
Ribeiro NQ, Santos APN, Emídio ECP, Costa MC, Freitas GJC, Carmo PHF, Silva MF, de Brito CB, de Souza DG, Paixão TA, Santos DA. Ribeiro NQ, et al. Int J Antimicrob Agents. 2019 Sep;54(3):301-308. doi: 10.1016/j.ijantimicag.2019.06.020. Epub 2019 Jul 3. Int J Antimicrob Agents. 2019. PMID: 31279153
The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection.
Freitas GJC, Gouveia-Eufrasio L, Emidio ECP, Carneiro HCS, de Matos Baltazar L, Costa MC, Frases S, de Sousa Araújo GR, Paixão TA, Sossai BG, Caza M, Kronstad JW, Peres NTA, Santos DA. Freitas GJC, et al. Among authors: emidio ecp. Cells. 2022 Dec 2;11(23):3896. doi: 10.3390/cells11233896. Cells. 2022. PMID: 36497155 Free PMC article.
Secondary Streptococcus pneumoniae infection increases morbidity and mortality during murine cryptococcosis.
Miranda BA, Freitas GJC, Leocádio VAT, Costa MC, Emídio ECP, Ribeiro NQ, Carmo PHF, Gouveia-Eufrásio L, Hubner J, Tavares LP, Arifa RDN, Brito CB, Silva MF, Teixeira MM, Paixão TA, Peres NTA, Fagundes CT, Santos DA. Miranda BA, et al. Among authors: emidio ecp. Immunology. 2024 Jan;171(1):92-103. doi: 10.1111/imm.13701. Epub 2023 Oct 9. Immunology. 2024. PMID: 37814467
17-β-Estradiol increases macrophage activity through activation of the G-protein-coupled estrogen receptor and improves the response of female mice to Cryptococcus gattii.
Costa MC, de Barros Fernandes H, Gonçalves GKN, Santos APN, Ferreira GF, de Freitas GJC, do Carmo PHF, Hubner J, Emídio ECP, Santos JRA, Dos Santos JL, Dos Reis AM, Fagundes CT, da Silva AM, Santos DA. Costa MC, et al. Among authors: emidio ecp. Cell Microbiol. 2020 Jun;22(6):e13179. doi: 10.1111/cmi.13179. Epub 2020 Feb 20. Cell Microbiol. 2020. PMID: 32017324
Randomized, phase 1/2, double-blind pioglitazone repositioning trial combined with antifungals for the treatment of cryptococcal meningitis - PIO study.
Gouveia-Eufrasio L, Ribeiro NQ, Santos JRA, da Costa MC, Emídio ECP, de Freitas GJC, do Carmo PHF, Miranda BA, de Oliveira JCMD, da Silva LMV, Teixeira Leocádio VA, Randi Magalhães VC, Penido I, Pereira LS, Rabelo LF, de Almeida Faria FA, Teixeira Dutra MR, Aspahan M, de Paula L, da Silva DI, Tavares Melo MG, de Andrade Zambelli VA, Gomes Faraco AA, da Costa César I, Alves GP, da Cunha Melo LF, de Aguiar Peres NT, Santos DA. Gouveia-Eufrasio L, et al. Contemp Clin Trials Commun. 2021 Feb 10;22:100745. doi: 10.1016/j.conctc.2021.100745. eCollection 2021 Jun. Contemp Clin Trials Commun. 2021. PMID: 33997457 Free PMC article.